Yazar "Kara, Emine Manolya" seçeneğine göre listele

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    A case of bartonellosis mimicking systemic lupus erythematosus
    (SAGE PUBLICATIONS LTD, 2022) Kara, Emine Manolya; Özdemir, Gül Nihal; Taşdemir, Mehmet; Ata, Serap; Karini, Belma; Valiyev, Eldar; Tutkun, İlknur Tuğal; Köse, Gülşen; Özkaya, Ozan
    Background and aim: Cat-scratch disease (CSD) is a systemic bacterial infection caused by Bartonella henselae. The disease is typically characterized by regional lymphadenopathy developing after scratches from domestic or feral cats. Rarely, systemic involvement may be observed. The co-occurrence with glomerulonephritis and positive antinuclear antibody (ANA) tests have been reported before. In these cases, the disease can be misdiagnosed as systemic lupus erythematosus. Ocular involvement occurs in 5%-10% of the cases with CSD, and neuroretinitis is among the common manifestations. Administration of corticosteroids (CSs) in addition to antibiotics has been shown to improve prognosis in neuroretinitis cases. However, the optimal dose and duration, remain ill-defined. Case report: In this article, we present an 11-year-old girl with CSD and neuroretinitis with a positive ANA test and hematuria, who benefited from high-dose methyl-prednisolone and antibiotics. Conclusion: Further research is warranted in order to determine the dose and duration of CSs in the treatment of Bartonella neuroretinitis.
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    Çocuklarda boğaz sürüntüsü örneği alımı
    (AVES YAYINCILIK, 2021) Kara, Emine Manolya
    Acute tonsillopharyngitis is the most commonly seen infection of the childhood leading to hospital presentations. The agent of the disease is mostly respiratory tract viruses. The most frequent bacterial agent group is Group A streptococcus (GAS), and GAS infections in school-aged children between 5 and 15 years have been reported as 15-30% among all tonsillopharyngitis agents. GAS pharyngitis can be observed in much younger children who are in contact with school-aged children. Corynebacterium diphtheriae, Neisseria gonorrhoeae, Arcanobacterium haemolyticum and anaerobe bacteria may also cause tonsillopharyngitis. While A. haemolyticum is a rare agent, it is substantial since it may lead to dengue-like rashes. Following the consumption of unpasteurized cow milk, Group C streptococcus may also be an agent of pharyngitis.
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    Correction to: primary antibody deficiencies in Turkey: molecular and clinical aspects
    (Springer, 2021) Fırtına, Sinem; Ng, Yuk Yin; Ng, Özden H.; Kıykım, Ayça; Yücel Özek, Esra; Kara, Emine Manolya; Kaya, Ayşenur
    The original published version of this article contained a mistake in one of the affiliations. The correct affiliation of author Manolya Kara (7) should read: Istinye University Faculty of Medicine, VM MedicalPark Pendik Hospital, Pediatric Infectious Diseases Clinic, Istanbul, Turkey The original article has been corrected. © 2021, Springer Science+Business Media, LLC, part of Springer Nature.
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    COVID-19 associated multisystemic inflammatory syndrome in 614 children with and without overlap with Kawasaki disease-Turk MIS-C study group
    (Springer, 2022) Yılmaz Çiftdoğan, Dilek; Ekemen Keleş, Yıldız; Şirvan Çetin, Benhur; Dalgıç Karabulut, Nazan; Sütçü, Murat; Kara, Emine Manolya
    Multisystemic inflammatory syndrome (MIS-C) diagnosis remains difficult because the clinical features overlap with Kawasaki disease (KD). The study aims to highlight the clinical and laboratory features and outcomes of patients with MISC whose clinical manifestations overlap with or without KD. This study is a retrospective analysis of a case series designed for patients aged 1 month to 18 years in 28 hospitals between November 1, 2020, and June 9, 2021. Patient demographics, complaints, laboratory results, echocardiographic results, system involvement, and outcomes were recorded. A total of 614 patients were enrolled; the median age was 7.4 years (interquartile range (IQR) 3.9-12 years). A total of 277 (45.1%) patients with MIS-C had manifestations that overlapped with KD, including 92 (33.3%) patients with complete KD and 185 (66.7%) with incomplete KD. Lymphocyte and platelet counts were significantly lower in patients with MISC, overlapped with KD (lymphocyte count 1080 vs. 1280 cells × ?L, p = 0.028; platelet count 166 vs. 216 cells × 103/?L, p < 0.001). The median serum procalcitonin levels were statistically higher in patients overlapped with KD (3.18 vs. 1.68 µg/L, p = 0.001). Coronary artery dilatation was statistically significant in patients with overlap with KD (13.4% vs. 6.8%, p = 0.007), while myocarditis was significantly more common in patients without overlap with KD features (2.6% vs 7.4%, p = 0.009). The association between clinical and laboratory findings and overlap with KD was investigated. Age > 12 years reduced the risk of overlap with KD by 66% (p < 0.001, 95% CI 0.217-0.550), lethargy increased the risk of overlap with KD by 2.6-fold (p = 0.011, 95% CI 1.244-5.439), and each unit more albumin (g/dl) reduced the risk of overlap with KD by 60% (p < 0.001, 95% CI 0.298-0.559).Conclusion: Almost half of the patients with MISC had clinical features that overlapped with KD; in particular, incomplete KD was present. The median age was lower in patients with KD-like features. Lymphocyte and platelet counts were lower, and ferritin and procalcitonin levels were significantly higher in patients with overlap with KD. What is Known: • In some cases of MIS-C, the clinical symptoms overlap with Kawasaki disease. • Compared to Kawasaki disease, lymphopenia was an independent predictor of MIS-C. What is New: • Half of the patients had clinical features that overlapped with Kawasaki disease. • In patients whose clinical features overlapped with KD, procalcitonin levels were almost 15 times higher than normal. • Lethargy increased the risk of overlap with KD by 2.6-fold in MIS-C patients. • Transient bradycardia was noted in approximately 10% of our patients after initiation of treatment.
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    Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male
    (Malawi Medical Journal, 2022) Sütçü, Murat; Gül, Doruk; Atik, Fatih; Kara, Emine Manolya
    Pfizer-BioNTech COVID-19 (BNT162b2) conferred a high level of protection against Covid-19 with a proven short-term safety profile. Although cases of vaccine-associated myopericarditis have been reported, the existence of rhabdomyolysis without myocarditis has not yet been published. A 16-year-old, healthy male patient, who did not use any herbal or illegal drugs before, was admitted with muscle pain that developed after the second dose of BNT162b2 vaccine. Cardiac examination and heart enzymes were normal and the patient had significantly higher creatinine kinase levels. The patient, whose enzymes returned to normal with only force hydration therapy, recovered without complications. Reporting the side effects of the vaccine, which has a short history of application to large populations, is of vital importance in the conduct of vaccine development studies and in identifying the risky group in terms of side effects. © 2022 The College of Medicine and the Medical Association of Malawi.
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    Successful treatment with therapeutic plasmapheresis of a pediatric patient with Guillain-Barré syndrome associated with neurobrucellosis
    (John Wiley and Sons Inc, 2022) Varol, Fatih; Yusuf Can, Yaşar; Şahin, Ebru Güney; Şahin, Süleyman Berkay; Akyüz, Gülcan; Aydın, Ali; Kara, Emine Manolya; Çam, Halit
    Brucellosis is a multisystemic disease that can present with multiple signs and symptoms. Rarely, brucellosis can manifest as neurobrucellosis, with central or peripheral nervous system involvement. Guillain-Barré syndrome (GBS) is a post-infectious autoimmune disease that progresses rapidly, causing ascending muscle weakness, and is accompanied by areflexia/hyporeflexia. Regarding GBS etiology, it is thought to be an autoimmune disease, triggered by a previous bacterial or viral infection. There are a few Brucella-associated GBS case reports in the literature and in our opinion, only one of them is a pediatric patient. Herein we reported a case of GBS associated with neurobrucellosis, who was successfully treated with therapeutic plasmapheresis (TP) due to poor response to IVIG treatment.
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    Throat swab procedure in children
    (AVES, 2021) Kara, Emine Manolya
    Acute tonsillopharyngitis is the most commonly seen in fection of the childhood leading to hospital presentations. The agent of the disease is mostly respiratory tract viruses. The most frequent bacterial agent group is Group A strep tococcus (GAS), and GAS infections in school-aged child ren between 5 and 15 years have been reported as 15-30% among all tonsillopharyngitis agents. GAS pharyngitis can be observed in much younger children who are in contact with school-aged children. Corynebacterium diphtheriae, Neisseria gonorrhoeae, Arcanobacterium haemolyticum and anaerobe bacteria may also cause tonsillopharyngitis. While A. hae molyticum is a rare agent, it is substantial since it may lead to dengue-like rashes. Following the consumption of unpasteu rized cow milk, Group C streptococcus may also be an agent of pharyngitis.