Successful treatment with therapeutic plasmapheresis of a pediatric patient with Guillain-Barré syndrome associated with neurobrucellosis

Özet

Brucellosis is a multisystemic disease that can present with multiple signs and symptoms. Rarely, brucellosis can manifest as neurobrucellosis, with central or peripheral nervous system involvement. Guillain-Barré syndrome (GBS) is a post-infectious autoimmune disease that progresses rapidly, causing ascending muscle weakness, and is accompanied by areflexia/hyporeflexia. Regarding GBS etiology, it is thought to be an autoimmune disease, triggered by a previous bacterial or viral infection. There are a few Brucella-associated GBS case reports in the literature and in our opinion, only one of them is a pediatric patient. Herein we reported a case of GBS associated with neurobrucellosis, who was successfully treated with therapeutic plasmapheresis (TP) due to poor response to IVIG treatment.

Açıklama

Anahtar Kelimeler

Guillain-Barre, Neurobrucellosis, Plasma Exchange

Kaynak

Journal of Clinical Apheresis

WoS Q Değeri

Q4

Scopus Q Değeri

N/A

Cilt

37

Sayı

5

Künye

Varol, F., Yusuf Can, Y., Sahin, E., Sahin, S. B., Akyuz, G., Aydin, A., . . . Cam, H. (2022). Successful treatment with therapeutic plasmapheresis of a pediatric patient with guillain-barré syndrome associated with neurobrucellosis. Journal of Clinical Apheresis, 37(5), 522-526. doi:10.1002/jca.22020