Endothelial dysfunction is related to central retinal artery occlusion

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dc.authoridCigdem Ileri / 0000-0002-7974-9406
dc.authoridGizem Doğan Gökçe / 0000-0003-1328-7103
dc.authoridBatur Gonenc Kanar / 0000-0002-5156-0302
dc.authoridHatice Selen Kanar / 0000-0001-6505-9714
dc.authorwosidBatur Gonenc Kanar / MCJ-7603-2025
dc.contributor.authorIleri, Cigdem
dc.contributor.authorGökçe, Gizem Doğan
dc.contributor.authorKanar, Batur Gonenc
dc.contributor.authorKanar, Hatice Selen
dc.date.accessioned2025-04-18T09:25:27Z
dc.date.available2025-04-18T09:25:27Z
dc.date.issued09.10.2024
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractAim: Central retinal artery occlusion (CRAO) leads to significant, non-painful loss of sight due to retinal infarction. Most CRAO patients have atherosclerotic risk factors. Pulse wave velocity (PWV) and Flow-mediated dilatation (FMD) can provide insights into the onset and development of atherosclerosis. This research aims to assess arterial stiffness measures and identify endothelial dysfunction in individuals with CRAO. Materials and Methods: 33 consecutive CRAO patients (63 ± 7 years, 21 men (63.6%)) were recruited in the study. 35 age /sex-matched participants were included as a control group. FMD and PWV were measured from the brachial artery, as indicators of endothelial dysfunction and atherosclerosis in the arterial wall, respectively. Additionally, the transthoracic echocardiographic parameters of the patients were investigated. Results: CRAO patients had significantly higher frequencies of hypertension, hyperlipidemia, and smoking status. Furthermore, the frequency of diabetes was also higher in the CRAO group, but this difference did not reach statistical significance. CRAO patients showed markedly elevated PWV and reduced FMD. However, no notable differences were observed between groups in terms of left ventricle systolic and diastolic functions. Conclusion: Our study showed that CRAO patients may have increased arterial stiffness and endothelial dysfunction. Systemic endothelial dysfunction and atherosclerosis may be linked to the development of CRAO.
dc.identifier.citationILERI, C., GÖKÇE, G. D., KANAR, B. G., KANAR, H. S. (2024). Endothelial dysfunction is related to central retinal artery occlusion. Annals of Medical Research , 31(9), 741 - 746. doi.org/10.5455/annalsmedres.2024.07.158
dc.identifier.doi10.5455/annalsmedres.2024.07.158
dc.identifier.endpage746
dc.identifier.issue9
dc.identifier.startpage741
dc.identifier.trdizinid1266050
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1266050/endothelial-dysfunction-is-related-to-central-retinal-artery-occlusion
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6787
dc.identifier.volume31
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorKanar, Batur Gonenc
dc.institutionauthoridBatur Gonenc Kanar / 0000-0002-5156-0302
dc.language.isoen
dc.publisherNurettin Aydoğdu Ahmet Sarıcı Cuma Mertoğlu Emrah Gündüz Lokman Hekim Tanrıverdi Nurullah Dağ Osman Kurt Tevfik Tolga Şahin
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectArterial stiffness Endothelial dysfunction Flow-mediated dilatation Pulse wave velocity Central retinal artery occlusion
dc.subjectEndothelial dysfunction
dc.subjectFlow-mediated dilatation Pulse wave velocity Central retinal artery occlusion
dc.subjectPulse wave velocity
dc.subjectCentral retinal artery occlusion
dc.titleEndothelial dysfunction is related to central retinal artery occlusion
dc.typeArticle

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