Prognostic factors affecting survival in breast cancer patients age 40 or younger

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dc.authoridCan Akgün / 0000-0002-8367-0768en_US
dc.authoridNecati Özen / 0000-0002-8072-9234en_US
dc.authorscopusidCan Akgün / 57219778461en_US
dc.authorscopusidNecati Özen / 6602743597en_US
dc.authorwosidNecati Özen / FUI-3304-2022
dc.contributor.authorKuru, Bekir
dc.contributor.authorYürüker, Savaş
dc.contributor.authorAkgün, Can
dc.contributor.authorKarabacak, Ufuk
dc.contributor.authorÖzen, Necati
dc.date.accessioned2022-12-23T09:52:04Z
dc.date.available2022-12-23T09:52:04Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Hastaneen_US
dc.description.abstractThe aims of this study were to identify the factors affecting survival and disease-free survival (DFS) in invasive breast cancer patients who underwent surgery for breast cancer age 40 or younger. Medical records of 216 women with breast carcinoma at age 40 or younger who underwent surgery at our Institution between October 2005 and May 2017 were retrospectively reviewed. One hundred and eighty eight invasive breast cancer patients that were eligible were categorized according to their clinical and pathological features. Univariate analyses of survival and DFS were performed by the Kaplan-Meier method and the log-rank test. Independent prognostic and predictive factors affecting survival and DFS were assessed by Cox regression proportional hazard method. 10-year survival and DFS were 85 and 74%, respectively. Axillary involvement, pathologic tumor size, HER 2 + subtype and Triple Negative subtype were found to be the prognostic factors that independently affected survival and DFS. The prognosis is worse in patients with axillary involvement, tumors larger than 2 cm, and HER 2+ and Triple Negative subtypes. These adverse prognostic factors should be considered during treatment and follow-up of patients age 40 or younger. © 2022 Ondokuz Mayis Universitesi. All rights reserved.en_US
dc.identifier.citationAKGÜN, C., Bekir, K. U. R. U., YÜRÜKER, S. S., KARABACAK, U., & Necati, Ö. Z. E. N. (2022). Prognostic factors affecting survival in breast cancer patients age 40 or younger. Journal of Experimental and Clinical Medicine, 39(4), 928-933.en_US
dc.identifier.doi10.52142/omujecm.39.4.2en_US
dc.identifier.endpage933en_US
dc.identifier.issn1309-4483en_US
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85142454724en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage928en_US
dc.identifier.urihttp://dx.doi.org/10.52142/omujecm.39.4.2
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3776
dc.identifier.volume39en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorAkgün, Can
dc.institutionauthorÖzen, Necati
dc.language.isoenen_US
dc.publisherOndokuz Mayis Universitesien_US
dc.relation.ispartofJournal of Experimental and Clinical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast Canceren_US
dc.subjectBreast Neoplasmsen_US
dc.subjectDisease-Free Survivalen_US
dc.subjectPrognosisen_US
dc.subjectSurvivalen_US
dc.titlePrognostic factors affecting survival in breast cancer patients age 40 or youngeren_US
dc.typeArticleen_US

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