Antioxidant and antimicrobial activities of various extracts from Stachys cretica subsp. bulgarica Rech.f., Stachys byzantina K. Koch and Stachys thirkei K. Koch

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dc.authoridGizem Gülsoy Toplan / 0000-0002-0544-2532
dc.authorscopusidGizem Gülsoy Toplan / 57192304526
dc.authorwosidGizem Gülsoy Toplan / ECA-5991-2022
dc.contributor.authorGülsoy Toplan, Gizem
dc.contributor.authorTaşkın, Turgut
dc.contributor.authorKara, Emel Mataracı
dc.contributor.authorGenç, Gülay Ecevit
dc.date.accessioned2022-02-02T12:51:45Z
dc.date.available2022-02-02T12:51:45Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümüen_US
dc.description.abstractBackground and Aims: Stachys L. species, which are members of the Lamiaceae family, have long been applied for their therapeutic benefits especially to cure cough, infection, genital tumors, ulcers, inflammatory illnesses, and wounds in Anatolian traditional medicine. In the current study, various extracts prepared from the aerial parts of Stachys cretica subsp. butgarica Rech.f. (SC), Stachys byzantina K. Koch (SB), Stachys thirkei K. Koch and were tested for their in vitro antioxidant, antibacterial, and anticandidat properties. Methods: The aerial parts of three Stachys species were sequentially extracted using n-hexane, chloroform, and methanol. Aqueous extracts of each sample was also prepared by infusion process. The total phenolic content of each extract was determined and the contribution of the biological activities in the samples was evaluated. To assess the antioxidant capacity, samples were studied using CUPRAC activity, DPPH center dot free radical scavenging, and FRAP methods. The antimicrobial activity of the extracts was tested against 7 bacteria and 3 yeast. Results: The infusion and methanol extract exhibited the strongest antioxidant potential and also had the highest percentage of phenolics among the studied extracts. The n-hexane extracts of all studied species showed considerable antifungal activity with MIC values ranging from 312.5-78.12 mg/L. Conclusion: According to our results, three Stachys species were found to be beneficial for their antioxidant and antimicrobial properties.en_US
dc.description.abstractBackground and Aims: Stachys L. species, which are members of the Lamiaceae family, have long been applied for their therapeutic benefits especially to cure cough, infection, genital tumors, ulcers, inflammatory illnesses, and wounds in Anatolian traditional medicine. In the current study, various extracts prepared from the aerial parts of Stachys cretica subsp. butgarica Rech.f. (SC), Stachys byzantina K. Koch (SB), Stachys thirkei K. Koch and were tested for their in vitro antioxidant, antibacterial, and anticandidat properties. Methods: The aerial parts of three Stachys species were sequentially extracted using n-hexane, chloroform, and methanol. Aqueous extracts of each sample was also prepared by infusion process. The total phenolic content of each extract was determined and the contribution of the biological activities in the samples was evaluated. To assess the antioxidant capacity, samples were studied using CUPRAC activity, DPPH center dot free radical scavenging, and FRAP methods. The antimicrobial activity of the extracts was tested against 7 bacteria and 3 yeast. Results: The infusion and methanol extract exhibited the strongest antioxidant potential and also had the highest percentage of phenolics among the studied extracts. The n-hexane extracts of all studied species showed considerable antifungal activity with MIC values ranging from 312.5-78.12 mg/L. Conclusion: According to our results, three Stachys species were found to be beneficial for their antioxidant and antimicrobial properties.en_US
dc.identifier.citationGulsoy Toplan, G., Taskin, T., Mataraci Kara, E., & Ecevit Genc, G. (2021). Antioxidant and antimicrobial activities of various extracts from Stachys cretica subsp. bulgarica Rech.f., Stachys byzantina K. Koch and Stachys thirkei K. Koch. İstanbul Journal of Pharmacy, 51(3), 341-347.en_US
dc.identifier.doi10.26650/IstanbulJPharm.2021.974035en_US
dc.identifier.endpage347en_US
dc.identifier.issn2587-2087en_US
dc.identifier.issue3en_US
dc.identifier.startpage341en_US
dc.identifier.urihttps://doi.org/10.26650/IstanbulJPharm.2021.974035
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2453
dc.identifier.volume51en_US
dc.identifier.wosWOS:000744167900009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorGülsoy Toplan, Gizem
dc.language.isoenen_US
dc.publisherIstanbul University Pressen_US
dc.relation.ispartofISTANBUL JOURNAL OF PHARMACYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectStachysen_US
dc.subjectAntioxidant Activityen_US
dc.subjectTotal Phenolicen_US
dc.subjectAntimicrobial Activityen_US
dc.titleAntioxidant and antimicrobial activities of various extracts from Stachys cretica subsp. bulgarica Rech.f., Stachys byzantina K. Koch and Stachys thirkei K. Kochen_US
dc.typeArticleen_US

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