30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA data

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dc.authoridÇağhan Pekşen / 0000-0003-3956-6282en_US
dc.authoridAziz Sümer / 0000-0003-3938-3363
dc.authoridOsman Anıl Savaş / 0000-0002-9698-5080
dc.authorscopusidÇağhan Pekşen / 57094191100
dc.authorscopusidAziz Sümer / 26653741600
dc.authorscopusidOsman Anıl Savaş / 56439426800
dc.authorwosidÇağhan Pekşen / AAT-3084-2020
dc.authorwosidAziz Sümer / JRV-1467-2023
dc.authorwosidOsman Anıl Savaş / AHE-7902-2022
dc.contributor.authorSinghal, Rishi
dc.contributor.authorCardoso, Victor Roth
dc.contributor.authorWiggins, Tom H.
dc.contributor.authorSuper, Jonathan T.
dc.contributor.authorLudwig, Christian
dc.contributor.authorSümer, Aziz
dc.contributor.authorPekşen, Çağhan
dc.contributor.authorSavaş, Osman Anıl
dc.date.accessioned2021-12-27T13:30:20Z
dc.date.available2021-12-27T13:30:20Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: There is a paucity of data comparing 30-day morbidity and mortality of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one anastomosis gastric bypass (OAGB). This study aimed to compare the 30-day safety of SG, RYGB, and OAGB in propensity score-matched cohorts. Materials and methods: This analysis utilised data collected from the GENEVA study which was a multicentre observational cohort study of bariatric and metabolic surgery (BMS) in 185 centres across 42 countries between 01/05/2022 and 31/10/2020 during the Coronavirus Disease-2019 (COVID-19) pandemic. 30-day complications were categorised according to the Clavien–Dindo classification. Patients receiving SG, RYGB, or OAGB were propensity-matched according to baseline characteristics and 30-day complications were compared between groups. Results: In total, 6770 patients (SG 3983; OAGB 702; RYGB 2085) were included in this analysis. Prior to matching, RYGB was associated with highest 30-day complication rate (SG 5.8%; OAGB 7.5%; RYGB 8.0% (p = 0.006)). On multivariate regression modelling, Insulin-dependent type 2 diabetes mellitus and hypercholesterolaemia were associated with increased 30-day complications. Being a non-smoker was associated with reduced complication rates. When compared to SG as a reference category, RYGB, but not OAGB, was associated with an increased rate of 30-day complications. A total of 702 pairs of SG and OAGB were propensity score-matched. The complication rate in the SG group was 7.3% (n = 51) as compared to 7.5% (n = 53) in the OAGB group (p = 0.68). Similarly, 2085 pairs of SG and RYGB were propensity score-matched. The complication rate in the SG group was 6.1% (n = 127) as compared to 7.9% (n = 166) in the RYGB group (p = 0.09). And, 702 pairs of OAGB and RYGB were matched. The complication rate in both groups was the same at 7.5 % (n = 53; p = 0.07). Conclusions: This global study found no significant difference in the 30-day morbidity and mortality of SG, RYGB, and OAGB in propensity score-matched cohorts.en_US
dc.identifier.citationSinghal, R., Cardoso, V. R., Wiggins, T., Super, J., Ludwig, C., Gkoutos, G. V., & Mahawar, K. (2021). 30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA data. International Journal of Obesity, 1-8.en_US
dc.identifier.doi10.1038/s41366-021-01048-1en_US
dc.identifier.issn0307-0565en_US
dc.identifier.scopus2-s2.0-85121334402en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1038/s41366-021-01048-1
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2358
dc.indekslendigikaynakScopusen_US
dc.institutionauthorSümer, Aziz
dc.institutionauthorPekşen, Çağhan
dc.institutionauthorSavaş, Osman Anıl
dc.language.isoenen_US
dc.publisherSpringer Natureen_US
dc.relation.ispartofInternational Journal of Obesityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.title30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA dataen_US
dc.typeArticleen_US

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