The effect of lactobacillus rhamnosus GG in infants with food protein-induced allergic proctocolitis

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dc.authorscopusidAyşenur Kaya / 55544555800
dc.authorwosidAyşenur Kaya / AAO-7577-2020
dc.contributor.authorAvcı, Özgecan
dc.contributor.authorUsta, Merve
dc.contributor.authorKaya, Ayşenur
dc.contributor.authorKaya, Nesrin
dc.contributor.authorUrgancı, Nafiye
dc.date.accessioned2025-05-08T10:41:50Z
dc.date.available2025-05-08T10:41:50Z
dc.date.issued2024
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBACKGROUND/AIMS: Most infants with food protein-induced allergic proctocolitis (FPIAP) achieve clinical tolerance between 1 and 3 years of age. The aim of this study was to investigate the effect of Lactobacillus rhamnosus GG on the development of tolerance in infants who are exclusively breastfed and diagnosed with FPIAP. MATERIALS AND METHODS: Sixty infants with FPIAP were divided into two groups: group 1 (study); who received probiotic Lactobacillus rhamnosus GG for 3 months, and group 2 (control); who did not. Clinical characteristics, allergy tests, and tolerance development were examined. RESULTS: Thirty patients [mean age: 3.9 +/- 1.3, range: 2-6 months, male/female (M/F): 1.7] in group 1 and 30 patients (mean age: 4.1 +/- 1.3, range: 1.4-6 months, M/F: 0.7) in group 2 were included in the study. The reintroduction of trigger foods into the mothers' diet at 9 months was significantly higher in group 1 than in group 2 (63.3% versus 26.7% of the patients, respectively, p=0.004). No significant difference was observed in terms of the resolution time of symptoms and time of tolerance development between groups and subgroups. CONCLUSION: A significant difference was observed in the mean time to reintroduce trigger foods into the maternal diet, the number of mothers who first reintroduced trigger foods back into their diet at 9 months, and the resolution of symptoms at 9 and 12 months in infants with multiple food allergies.
dc.identifier.citationAvcı, Ö., Usta, M., Kaya, A., Kaya, N., & Urgancı, N. (2024). The Effect of Lactobacillus rhamnosus GG in Infants with Food Protein-Induced Allergic Proctocolitis.
dc.identifier.doi10.4274/cjms.2024.2024-17
dc.identifier.endpage331
dc.identifier.issn2149-7893
dc.identifier.issn2536-507X
dc.identifier.issue5
dc.identifier.startpage323
dc.identifier.urihttp://dx.doi.org/10.4274/cjms.2024.2024-17
dc.identifier.urihttps://hdl.handle.net/20.500.12713/7234
dc.identifier.volume9
dc.identifier.wosWOS:001354630700001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorKaya, Ayşenur
dc.institutionauthoridAyşenur Kaya / 0000-0002-8183-0190
dc.language.isoen
dc.publisherGalenos publishing house
dc.relation.ispartofCyprus journal of medical sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectFood Protein-Induced Allergic Proctocolitis
dc.subjectLactobacillus Rhamnosus GG
dc.subjectProbiotics
dc.subjectTolerance
dc.subjectTreatment
dc.titleThe effect of lactobacillus rhamnosus GG in infants with food protein-induced allergic proctocolitis
dc.typeArticle

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