Genomic and proteomic monitoring of stem cell-derived exosomes

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dc.authoridErdal Karaƶz / 0000-0002-9992-833Xen_US
dc.authoridEda Sun / 0000-003-0320-5784en_US
dc.authorscopusidErdal Karaƶz / 7003448087
dc.authorscopusidEda Sun / 57225054414
dc.authorwosidErdal Karaƶz / IXE-6677-2023
dc.authorwosidEda Sun / GER-0120-2022
dc.contributor.authorKaraƶz, Erdal
dc.contributor.authorSun, Eda
dc.date.accessioned2020-10-07T08:14:26Z
dc.date.available2020-10-07T08:14:26Z
dc.date.issued2019
dc.departmentÄ°stinye Ɯniversitesi, Tıp FakĆ¼ltesi, Temel Tıp Bilimleri BƶlĆ¼mĆ¼en_US
dc.description.abstractThe mesenchymal stem cell (MSC) transplantations are increasing day by day in clinical therapies. Recent studies have described that the treatment activities of MSCs are mediated by paracrine factors secreted. These paracrine factors are spread through messenger clouds as exosomes secreted from MSCs, which are also involved in the cellular communication via transferring their mRNA, miRNA, and protein contents horizontally. With the understanding of this mechanism, cell-free therapies have begun to create a new path in MSC based therapies as a cell-free treatment. It is important to understand how much the mRNA, miRNA, and protein contents of the MSCs and their secreted exosomes are overlapping. Additionally, the content of these exosomes must be determined in order to both define their efficacy and to be able to select their most suitable sources. Therefore, in this chapter, we have described different transcriptomic and proteomic methods for displaying the contents of the exosomes.en_US
dc.identifier.citationKaraƶz, E., & Sun, E. (2019). Genomic and Proteomic Monitoring of Stem Cell-Derived Exosomes. In Genomics, Proteomics, and Metabolomics (pp. 97-106). Humana, Cham.en_US
dc.identifier.doi10.1007/978-3-030-27727-7_5en_US
dc.identifier.endpage106en_US
dc.identifier.startpage97en_US
dc.identifier.urihttps://doi.org/10.1007/978-3-030-27727-7_5
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1133
dc.identifier.wosWOS:000572058900006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorKaraƶz, Erdal
dc.institutionauthorSun, Eda
dc.language.isoenen_US
dc.publisherHUMANA PRESS INCen_US
dc.relation.ispartofGENOMICS, PROTEOMICS, AND METABOLOMICS: STEM CELLS MONITORING IN REGENERATIVE MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Ɩğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMesenchymal Stem Cell Derive Exosomesen_US
dc.subjectCell-Free Therapiesen_US
dc.subjectTranscriptomeen_US
dc.subjectProteomeen_US
dc.titleGenomic and proteomic monitoring of stem cell-derived exosomesen_US
dc.typeArticleen_US

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