Haplotypes rich in activating killer-cell immnuglobulin-like receptor genes are associated with delay on age of myeloma onset

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Küçük Resim

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

CIG MEDIA GROUP

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Natural killer (NK) cells are known for their anti-tumoral cytotoxic effects. Effector NK-cell functions are controlled by interactions between inhibitory and activating killer-cell immnuglobulin-like receptors (iKIRs and aKIRs) on NK cells in the presence of human leukocyte antigen (HLA) class I ligands on target cells. The aim of this study was to investigate the frequency of KIR genotypes with/without their cognate ligands among myeloma (MM) patients compared to a healthy population.

Açıklama

Anahtar Kelimeler

Kaynak

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

WoS Q Değeri

Q3

Scopus Q Değeri

Cilt

21

Sayı

Supplement 2

Künye

Akin, H. Y., Seval, G. C., Atilla, P. A., Mesutoglu, P. Y., Otlu, T., Anliacik, R., ... & Beksac, M. (2021). P-068: Haplotypes rich in activating killer-cell immnuglobulin-like receptor genes are associated with delay on age of myeloma onset. Clinical Lymphoma Myeloma and Leukemia, 21, S76.