Exosomal circular RNAs (circRNAs) in cancer progression and diagnosis

Basit Öğe Kaydı
dc.contributor.authorRaesi, R.
dc.contributor.authorSaghari, S.
dc.contributor.authorBassiri, F.
dc.contributor.authorMotahhary, M.
dc.contributor.authorSalimimoghadam, S.
dc.contributor.authorCoskun, A.
dc.contributor.authorZarrabi A.
dc.date.accessioned2024-05-19T14:34:45Z
dc.date.available2024-05-19T14:34:45Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractOne of the diseases affecting and threatening the survival of human life is cancer. Cancer originates from a variety of factors and underlying mechanisms including environmental factors, exposure to toxic chemicals, lifestyle, inactivity, alteration in gene expression, and epigenetic changes. Circular RNAs (circRNAs) are endogenous RNA molecules with covalently closed loop structure and demonstrate high stability due to the resistance to RNase enzymes. They have more expression compared to linear RNA molecules and are potential biomarkers in cancer. Exosomes are small extracellular vesicles that can be secreted by different cells such as tumor cells, normal cells, macrophages, and cancer-associated fibroblasts that contain proteins, lipid and RNA molecules, and even DNA fragments. Dysregulation of circRNAs has been implicated in disease pathogenesis, especially cancer development and initiation. This chapter demonstrates the role of exosomal circRNAs in affecting the growth and invasion of tumor cells, and they can also be used as diagnostic and prognostic factors in cancer. © 2023 World Scientific Publishing Company. All rights reserved.en_US
dc.identifier.doi10.1142/9789811267390_0012
dc.identifier.endpage356en_US
dc.identifier.isbn9789811267406
dc.identifier.isbn9789811267383
dc.identifier.scopus2-s2.0-85163026355en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage319en_US
dc.identifier.urihttps://doi.org/10.1142/9789811267390_0012
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4546
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWorld Scientific Publishing Co.en_US
dc.relation.ispartofNon-coding RNA Transcripts In Cancer Therapy: Pre-clinical And Clinical Implicationsen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.titleExosomal circular RNAs (circRNAs) in cancer progression and diagnosisen_US
dc.typeBook Chapteren_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu