TRPV1 channel is a potential drug discovery channel for epilepsy
Yükleniyor...
Dosyalar
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
DergiPark
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Epilepsy is one of the most frequent and heterogeneous neurological disorders and it is characterized by several disabilities. Epilepsy is affecting about 3% of people worldwide. Current antiepileptic drugs are only effective in 60% of individuals and many drugs can induce several unwanted side effects in patients. Etiology of epilepsy has not been clarified fully. However, increased intracellular calcium ion (Ca2+) concentration has main role in etiology of epilepsy. Ca2+ passes the cell membrane through different cell membrane channels. One of the channels is TRP superfamily.
Açıklama
Anahtar Kelimeler
Epilepsy, TRPV1 Channels, Capsaicin, Oxidative Stress
Kaynak
J Cell Neurosci Oxid Stress
WoS Q Değeri
Scopus Q Değeri
Cilt
10
Sayı
3
Künye
Özşimşek, A . (2018). TRPV1 channel is a potential drug discovery channel for epilepsy . Journal of Cellular Neuroscience and Oxidative Stress , 10 (3) , 786-786 . DOI: 10.37212/jcnos.610113
