Effectiveness of preemptive chlorhexidine digluconate-flurbiprofen spray on postoperative sore throat and hoarseness in patients undergoing rhinoplasty: a retrospective study

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dc.authoridFatma Ferda Kartufan / 0000-0002-5592-2366en_US
dc.authoridMüslüm Çiçek / 0000-0001-9187-8342en_US
dc.authorscopusidFatma Ferda Kartufan / 56716406500en_US
dc.authorwosidFatma Ferda Kartufan / HGC-4836-2022en_US
dc.authorwosidMüslüm Çiçek / P-5252-2019en_US
dc.contributor.authorKartufan, Fatma Ferda
dc.contributor.authorYıldırım, Alpaslan
dc.contributor.authorMorkoç, Okan
dc.contributor.authorÇiçek, Müslüm
dc.date.accessioned2022-12-08T07:58:03Z
dc.date.available2022-12-08T07:58:03Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Hastaneen_US
dc.description.abstractBackground In this retrospective study, we aimed to investigate the effect of chlorhexidine digluconate-flurbiprofen spray (Klorhex Plus® oral spray) on postoperative sore throat (POST) and hoarseness (POH) in patients undergoing rhinoplasty. Methodology Patients who underwent rhinoplasty alone in our clinic between April 01, 2021, and February 28, 2022, were enrolled in the study. Patients' demographics such as age, gender, height, and smoking status that could affect sore throat, difficult intubation, and operation time were recorded from the patients' files. Patients were grouped as those who received Klorhex Plus oral spray before the surgery (Klorhex P group) and those who did not (control group). POST and POH were recorded from the patients' postoperative surgery files. Postoperative pain evaluation was performed using the Numerical Rating Scale (NRS) at the postoperative first hour (PPL1h), 12th hour (PPL12h), and first day (PPL1d) from the postoperative nursing files. Results A total of 354 patients who underwent rhinoplasty alone were included in this study. No significant difference was found between the groups in terms of the demographic data. Statistically, PPL1h, PPL12h, and PPL1d were significantly lower in the Klorhex P group compared to the control group (for all, p < 0.001). POST and POH were also significantly higher in the control group (both, p < 0.001). Conclusions The results of this study indicate that Klorhex Plus oral spray is an efficient agent for preemptive analgesia before rhinoplasty. It significantly decreases the postoperative pain level, POST, and POH. However, further comprehensive prospective studies are needed to introduce Klorhex Plus oral spray to rhinology practice.en_US
dc.identifier.citationKartufan FF, Yildirim A, Morkoc O, Çiçek M. Effectiveness of Preemptive Chlorhexidine Digluconate-Flurbiprofen Spray on Postoperative Sore Throat and Hoarseness in Patients Undergoing Rhinoplasty: A Retrospective Study. Cureus. 2022 Sep 22;14(9):e29448. doi: 10.7759/cureus.29448. PMID: 36299918; PMCID: PMC9587711.en_US
dc.identifier.doi10.7759/cureus.29448en_US
dc.identifier.issue9en_US
dc.identifier.pmid36299918en_US
dc.identifier.urihttps://doi.org/ 10.7759/cureus.29448
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3420
dc.identifier.volume14en_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKartufan, Fatma Funda
dc.institutionauthorÇiçek, Müslüm
dc.language.isoenen_US
dc.publisherPMC PubMed Centralen_US
dc.relation.ispartofCureusen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChlorhexidine Digluconateen_US
dc.subjectFlurbiprofenen_US
dc.subjectHoarsenessen_US
dc.subjectPreemptive Analgesiaen_US
dc.subjectRhinoplastyen_US
dc.subjectSore Throaten_US
dc.titleEffectiveness of preemptive chlorhexidine digluconate-flurbiprofen spray on postoperative sore throat and hoarseness in patients undergoing rhinoplasty: a retrospective studyen_US
dc.typeArticleen_US

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