Biological evaluation of stachys iberica subsp. stenostachya (boiss.) rech.f. And scutellaria orientalis subsp. sosnowskyi (takht.) fed. growing in eastern anatolia

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dc.authoridGizem Gülsoy Toplan / 0000-0002-0544-2532
dc.authorscopusidGizem Gülsoy Toplan / 57192304526en_US
dc.authorwosidGizem Gülsoy Toplan / ECA-5991-2022
dc.contributor.authorGülsoy Toplan, Gizem
dc.contributor.authorCivas, Ayse
dc.contributor.authorMataracı-Kara, Emel
dc.contributor.authorTaşkın, Turgut
dc.contributor.authorGenç, Gülay Ecevit
dc.date.accessioned2021-12-27T06:12:11Z
dc.date.available2021-12-27T06:12:11Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümüen_US
dc.description.abstractSciVal Topics Metrics Abstract Lamiaceae is one of the largest families in the plant kingdom, including the genus Stachys and Scutellaria, which are used in many folk medicines throughout the world for the prevention and also the treatment of several disorders. In vitro biological potential of Stachys iberica subsp. stenostachya and Scutellaria orientalis subsp. sosnowskyi were investigated in the current study. The aerial parts of the plants were extracted using different solvents such as n-hexane, chloroform, and methanol. In addition, infusions of each plant were prepared. The antioxidant potential of the samples was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), ABTS assays, ferrous ion-chelating, and ferric reducing antioxidant power (FRAP) assays. Anticholinesterase activity of the extracts was also determined. Spectrophotometric analysis was used to assess the total phenolic content of the samples. The antimicrobial activities of samples were determined by minimal inhibitory concentration (MIC) against seven bacteria and three Candida spp. yeast. According to the findings, the infusion demonstrated significant antioxidant properties, whilst the extracts demonstrated high-to-moderate antioxidant effects. The n-hexane extracts showed higher antifungal activity against C.parapsilosis and C.tropicalis. These outcomes suggest that these two species from Turkey could be employed in the manufacture of phytopharmaceuticals.en_US
dc.identifier.citationToplan, G. G., CİVAŞ, A., Kara, E. M., TAŞKIN, T., & GENÇ, G. E. (2021). Biological evaluation of Stachys iberica subsp. stenostachya (Boiss.) Rech. f. and Scutellaria orientalis subsp. sosnowskyi (Takht.) Fed. growing in eastern Anatolia. International Journal of Secondary Metabolite, 8(4), 364-375.en_US
dc.identifier.doi10.21448/ijsm.979820en_US
dc.identifier.endpage375en_US
dc.identifier.issn2148-6905en_US
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85120816133en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage364en_US
dc.identifier.urihttps://doi.org/10.21448/ijsm.979820
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2342
dc.identifier.volume8en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorGülsoy Toplan, Gizem
dc.language.isoenen_US
dc.publisherPamukkale Universityen_US
dc.relation.ispartofInternational Journal of Secondary Metaboliteen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcetylcholinesteraseen_US
dc.subjectAntimicrobialen_US
dc.subjectAntioxidanten_US
dc.subjectLamiaceaeen_US
dc.subjectTurkeyen_US
dc.titleBiological evaluation of stachys iberica subsp. stenostachya (boiss.) rech.f. And scutellaria orientalis subsp. sosnowskyi (takht.) fed. growing in eastern anatoliaen_US
dc.typeArticleen_US

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