Comparing Loop and Divided Colostomy for Anorectal Malformation: A Systematic Review and Meta-Analysis

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dc.authorscopusidMustafa Azizoğlu / 58901683600
dc.authorwosidMustafa Azizoğlu / HKV-3601-2023
dc.contributor.authorGerçel, Gonca
dc.contributor.authorAzizoğlu, Mustafa
dc.contributor.authorKarakaş, Esra
dc.contributor.authorRisteski, Toni
dc.date.accessioned2025-04-18T10:25:42Z
dc.date.available2025-04-18T10:25:42Z
dc.date.issued2025
dc.departmentİstinye Üniversitesi, Lisansüstü Eğitim Enstitüsü, Sağlık Bilimleri, Kök Hücre ve Doku Mühendisliği Programı
dc.description.abstractIntroduction: The optimal type of colostomy for patients with anorectal malformations (ARM) remains unclear. We conducted a systematic review and meta-analysis to compare the clinical outcomes of loop colostomies (LC) versus divided colostomies (DC) in patients with ARM. Methods: After review registration (PROSPERO: CRD42024513335), we searched multiple databases for comparative studies on LCs and DCs in patients with ARMs. Gray literature was sought. The complications examined included stoma prolapse, urinary tract infection (UTI), skin excoriation, stoma retraction, parastomal hernia, wound infection rate, and stoma stricture. Three reviewers independently assessed the eligibility and quality of the included studies. Meta-analysis of selected complications was performed using Revman 5.4, with p < 0.05 considered significant. Results: Eleven studies were included in the analysis, incorporating a total of 2550 neonates with ARMs, of which 1147 underwent LCs and 1403 underwent DCs. The meta-analysis revealed no significant differences between the two groups in the incidence of stoma prolapse (OR: 1.55, 95 % CI: 0.63 to 3.79; p = 0.34), UTIs (OR: 1.78, 95 % CI: 0.50 to 6.36; p = 0.38), skin excoriation (OR: 1.26, 95 % CI: 0.68 to 2.34; p = 0.46), stoma retraction (OR: 0.79, 95 % CI: 0.09 to 6.64; p = 0.83), parastomal hernia (OR: 0.99, 95 % CI: 0.22 to 4.48; p = 0.99), wound infection (OR: 0.35, 95 % CI: 0.10 to 1.20; p = 0.10), and stoma stricture (OR: 0.70, 95 % CI: 0.22 to 2.18; p = 0.53). Conclusions: The findings suggest that LCs and DCs are viable options for fecal diversion, presenting similar risks and benefits. The choice between these techniques should consider individual patient characteristics and surgical expertise. Type of Study: Meta-analysis. Level of evidence: II. © 2024 Elsevier Inc.
dc.identifier.citationGerçel, G., Azizoglu, M., Karakas, E., Risteski, T., Escolino, M., & De La Torre, L. (2024). Comparing Loop and Divided Colostomy for Anorectal Malformation: A Systematic Review and Meta-Analysis. Journal of Pediatric Surgery, 161974.
dc.identifier.doi10.1016/j.jpedsurg.2024.161974
dc.identifier.issn00223468
dc.identifier.issue1
dc.identifier.pmid39358082
dc.identifier.scopus2-s2.0-85205451766
dc.identifier.scopusqualityQ1
dc.identifier.urihttp://dx.doi.org/10.1016/j.jpedsurg.2024.161974
dc.identifier.urihttps://hdl.handle.net/20.500.12713/7059
dc.identifier.volume60
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAzizoğlu, Mustafa
dc.institutionauthoridMustafa Azizoğlu / 0009-0000-3563-1230
dc.language.isoen
dc.publisherW.B. Saunders
dc.relation.ispartofJournal of Pediatric Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAnorectal Malformation
dc.subjectColostomy
dc.subjectDivided
dc.subjectLoop
dc.subjectMeta-Analysis
dc.titleComparing Loop and Divided Colostomy for Anorectal Malformation: A Systematic Review and Meta-Analysis
dc.typeArticle

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