The use of incisional negative-pressure wound therapy on high-risk patients with breast cancer after mastectomy

dc.authorscopusidEbru Esen / 57204694764
dc.authorwosidEbru Esen / U-4613-2018
dc.contributor.authorEsen, Ebru
dc.contributor.authorMorkavuk, Şevket Barış
dc.contributor.authorTuran, Müjdat
dc.contributor.authorAkyüz, Simay
dc.contributor.authorGüler, Sümeyra
dc.contributor.authorAkgül, Gökhan Giray
dc.contributor.authorBahçecioğlu, İbrahim Burak
dc.contributor.authorGülçelik, Mehmet Ali
dc.contributor.authorYılmaz, Kerim Bora
dc.date.accessioned2025-04-18T08:59:24Z
dc.date.available2025-04-18T08:59:24Z
dc.date.issued2025
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractBackground: The main complications seen in patients who have undergone modified radical mastectomy (MRM) are seroma, surgical site infection, hematoma, wound dehiscence, flap necrosis, and nerve damage. While these complications lead to some problems the most feared effect in the early period is that they cause a delay in adjuvant treatment. Incisional Negative Pressure Wound Therapy (iNPWT) decreases wound dehiscence by reducing oedema and tension, especially in the incision line. This study aim to compare recovery times and wound site complications between patients treated with conventional wound dressings and patients treated with iNPWT after MRM. Methods: A retrospective screening was made of the data of 50 patients who underwent MRM because of breast cancer in the General Surgery Clinic of XXX Hospital between 2018 and 2022, and were at high-risk of wound site complications. Two groups were formed as 30 patients applied with iNPWT and 20 patients applied with conventional dressings. Results: The mean age of the 50 female patients was 53.58 years (range, 30–80 years). The most frequently seen complications were seroma (20 patients) and partial flap ischaemia (14 patients). The mean number of iNPWT applications was 1.30 (range, 1–2), and the mean number of days of application was 4.47 (range, 2–9). Postoperative seroma was observed in 8 patients in the iNPWT group and in 12 patients in the conventional dressings group (p = 0.018). Flap ischaemia and the probability of dehiscence was determined at a statistically significantly higher rate in the patients in the conventional dressings groups (p = 0.005, p = 0.021). Conclusion: The results of this study demonstrated that the use of iNPWT significantly reduced the amount of postoperative drainage, thereby contributing to early drain removal. Furthermore, iNPWT significantly reduced postoperative seroma, flap ischaemia, and flap dehiscence compared to conventional dressings.
dc.identifier.citationEsen, E., Morkavuk, S. B., Turan, M., Akyuz, S., Guler, S., Akgul, G. G., ... & Yilmaz, K. B. (2024). The use of incisional negative pressure wound therapy on high-risk breast cancer mastectomy patients. Asian Journal of Surgery.
dc.identifier.doi10.1016/j.asjsur.2024.07.333
dc.identifier.endpage192
dc.identifier.issn10159584
dc.identifier.issue1
dc.identifier.pmid39164174
dc.identifier.scopus2-s2.0-85201456352
dc.identifier.scopusqualityQ2
dc.identifier.startpage185
dc.identifier.urihttp://dx.doi.org/10.1016/j.asjsur.2024.07.333
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6656
dc.identifier.volume48
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorEsen, Ebru
dc.institutionauthoridEbru Esen / 0000-0003-3019-0872
dc.language.isoen
dc.publisherElsevier (Singapore) Pte ltd
dc.relation.ispartofAsian journal of surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBreast Cancer
dc.subjectIncisional Negative Pressure Wound Therapy
dc.subjectiNPWT
dc.subjectSeroma
dc.subjectWound Complications
dc.titleThe use of incisional negative-pressure wound therapy on high-risk patients with breast cancer after mastectomy
dc.typeArticle

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