Relationship between platelet to lymphocyte ratio and coronary angiography timing in patients with NSTEMI

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dc.authoridSabri Seyis / 0000-0002-7980-0363
dc.authorscopusidŞeyda Günay / 55988316300
dc.authorscopusidSabri Seyis / 16176780400
dc.authorwosidSabri Seyis / F-7029-2014
dc.contributor.authorSeyis, Sabri
dc.contributor.authorGünay, Şeyda
dc.contributor.authorRencuzoğlu, İbrahim
dc.date.accessioned2020-08-30T20:01:40Z
dc.date.available2020-08-30T20:01:40Z
dc.date.issued2017
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionSeyis, Sabri (isu author)
dc.descriptionGunay, Seyda (isu author)
dc.descriptionRencuzoglu, Ibrahim (isu author)
dc.description.abstractObjective: To investigate the usefulness of PLR in predicting severity and complexity of coronary atherosclerosis as assessed by the SXscore in patients with Non ST elevation myocardial infarction NSTEMI who underwent nonurgent coronary angiography (CA). Background: In NSTEMI patients, there is a debate whether early angiography and revascularization is beneficial compared with a more conservative approach. Platelet to lymphocyte ratio (PLR) is a new prognostic marker that gives idea about inflammation and aggregation pathways and may predict coronary atherosclerotic burden. PLR can be used to select patients who should go under angiography earlier due to excessive ischemic load. Methods: We retrospectively evaluated 111 consecutive patients who presented with NSTEMI and underwent non-urgent coronary angiography between July 2016 and March 2017. The PLR was calculated as the ratio of the platelet count to the lymphocyte count. The Syntax scores SX of all patients were calculated. A low SX score was defined as ? 22, an intermediate score as 23 to 32, and a high score as ? 33. Results: 92 patients (82.8%) had low SX scores (? 22), 19 patients (17.1%) had intermediate to high SX scores (? 23). Patients in the intermediate to high SX score group had significantly higher PLR 263 (219-366) vs. 117 (82-144.5) p<0.001. In ROC analysis PLR of 178 or lower predicted a low SX score defined as ? 22 with a sensitivity of 91.3% and specificity of 100%. Conclusion: In patients with NSTEMI, PLR has significant association with syntax score and may be used for risk stratification and assessing optimal timing for coronary angiography. © 2017, Scientific Publishers of India, All rights reserved.en_US
dc.identifier.citationSeyis, S., Gunay, S., & Rencuzoglu, I. (2017). Relationship between platelet to lymphocyte ratio and coronary angiography timing in patients with NSTEMI.en_US
dc.identifier.endpage8968en_US
dc.identifier.issn0970938Xen_US
dc.identifier.issue20en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage8963en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12713/353
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorSeyis, Sabrien_US
dc.institutionauthorGünay, Şeydaen_US
dc.institutionauthorRencuzoğlu, İbrahimen_US
dc.language.isoenen_US
dc.publisherScientific Publishers of Indiaen_US
dc.relation.ispartofBiomedical Research (India)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLymphocyteen_US
dc.subjectNstemien_US
dc.subjectPlateleten_US
dc.subjectSyntax Scoreen_US
dc.titleRelationship between platelet to lymphocyte ratio and coronary angiography timing in patients with NSTEMIen_US
dc.typeArticleen_US

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