Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals?

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dc.authoridHidayet Kayançiçek / 0000-0001-6493-5591
dc.authorscopusidHidayet Kayançiçek / 15837302900
dc.authorwosidHidayet Kayançiçek / DUY-5949-2022
dc.contributor.authorYılmaz, Mücahid
dc.contributor.authorKayançiçek, Hidayet
dc.contributor.authorGözel, Nevzat
dc.contributor.authorKurtoğlu, Ertuğrul
dc.contributor.authorSeçen, Özlem
dc.contributor.authorÖner, Pınar
dc.contributor.authorÇekici, Yusuf
dc.contributor.authorBilen, Mehmet Nail
dc.contributor.authorDemirkıran, Suat
dc.contributor.authorUku, Ökkeş
dc.date.accessioned2020-09-24T13:53:17Z
dc.date.available2020-09-24T13:53:17Z
dc.date.issued2020en_US
dc.departmentİstinye Üniversitesien_US
dc.description.abstractIntroduction: Epicardial fat is a tissue that releases many proinflammatory and atherogenic mediators, with endocrine and paracrine effects on the heart. In this study, the implication of the EFT thickness (EFTt) on transmural dispersion of repolarisation (TDR) was analysed utilizing the T-wave peak to end interval (Tp-Te), the Tp-Te dispersion (Tp-Te (d)), and the Tp-Te/QT ratio. Material and methods: One thousand seven hundred and thirteen subjects were enrolled in the research. The subjects were chosen to be healthy individuals, without any cardiovascular/systemic disorders or risk factors for atherosclerosis. Transthoracic echocardiography (TTE) was applied to all subjects, and EFTt was measured in both diastole and systole. The ECG measurements were taken from standard 12-lead surface ECG. Results: Correlation analysis revealed that the EFTt is highly associated with the Tp-Te interval, Tp-Te/QT ratio, Tp-Te (d), increasing age, body mass index (BMI), body surface area (BSA), left ventricular (LV) mass, LV mass index, plasma glucose during fasting, triglycerides, and low-density lipoprotein cholesterol. Conclusions: The study results showed that increased EFTt was associated with increased TDR values of Tp-Te, Tp-Te (d), and Tp-Te/QT ratio, even in the absence of other factors that could increase TDR and EFTt. Therefore, it can be stated that increased EFTt may cause an increase the risk for ventricular arrhythmia.en_US
dc.identifier.citationYılmaz, M., Kayançiçek, H., Gözel, N., Kurtoğlu, E., Seçen, Ö., Öner, P., ... & Uku, Ö. (2020). Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals?. Archives of Medical sciences. Atherosclerotic Diseases, 5, e127.en_US
dc.identifier.doi10.5114/aoms.2020.96147en_US
dc.identifier.endpagee139en_US
dc.identifier.pmid32665987en_US
dc.identifier.startpagee127en_US
dc.identifier.urihttps://doi.org/10.5114/aoms.2020.96147
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1095
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKayançiçek, Hidayet
dc.language.isoenen_US
dc.relation.ispartofArch Med Sci Atheroscler Disen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFat Tissue of Epicardiumen_US
dc.subjectPredisposition to Ventricular Arrhythmiaen_US
dc.subjectRepolarisation Inhomogeneity of Ventricle.en_US
dc.titleIs there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals?en_US
dc.typeArticleen_US

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