Biocompatibility and toxicity challenges of nanomaterials
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Cancer is one of the most challenging diseases to treat and is one of the leading reasons for human death worldwide. In cancer research, nanomaterials are evaluated as an encouraging system due to their promising properties, consisting of nanoscale sizes and chemical and physical configurations that can be functionalized for the final application. Although much effort has been extended to efficient cancer research, the biocompatibility and toxicity of nanomaterials remain the main challenges. Cellular reactions are correlated with the physicochemical characteristics of nanomaterials. There are several structural parameters on which nanotoxicological reactions depend, such as size, charge, surface chemistry, and morphology. Notably, understanding the challenges is highly desirable to take full advantage of the benefits provided by nanomaterials. Therefore, this chapter covers the latest biocompatibility and toxicity findings from cancer studies using nanomaterials. Moreover, this chapter demonstrates the experiences learned and challenges faced by a group of leading scientists in this discipline. Also, it covers the physical, chemical, and biological strategies to make nanomaterials more biocompatible and nontoxic.
Açıklama
Anahtar Kelimeler
Biocompatibility, Cancer Research, Nanomaterial, Toxicity
Kaynak
Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Yaşayan, G., Alarcin, E., Avci-Adali, M., Ipek, T. C., Nejati, O., Özcan-Bülbül, E., ... & Mostafavi, E. (2024). Biocompatibility and toxicity challenges of nanomaterials. In Functionalized Nanomaterials for Cancer Research (pp. 603-631). Academic Press.
