Biocompatibility and toxicity challenges of nanomaterials

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dc.authorscopusidOmid Nejati / 58087746400
dc.authorscopusidEce Özcan Bülbül / 57211920637
dc.authorscopusidAyça Bal Öztürk / 57062000100
dc.authorwosidOmid Nejati / HKF-9791-2023
dc.authorwosidEce Özcan Bülbül / ACE-7724-2022
dc.authorwosidAyça Bal Öztürk / M-4472-2018
dc.contributor.authorYaşayan, Gökçen
dc.contributor.authorAlarçin, Emine
dc.contributor.authorAvcı Adalı, Meltem
dc.contributor.authorİpek, Tuba Çanak
dc.contributor.authorNejati, Omid
dc.contributor.authorÖzcan Bülbül, Ece
dc.contributor.authorKarslı, Seher
dc.contributor.authorÖztürk, Ayça Bal
dc.contributor.authorMostafavi, Ebrahim
dc.date.accessioned2025-04-18T08:14:02Z
dc.date.available2025-04-18T08:14:02Z
dc.date.issued2024
dc.departmentİstinye Üniversitesi, Lisansüstü Eğitim Enstitüsü, Sağlık Bilimleri, Kök Hücre ve Doku Mühendisliği Programı
dc.departmentİstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Teknolojisi Bölümü
dc.departmentİstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Temel Bilimleri Bölümü
dc.description.abstractCancer is one of the most challenging diseases to treat and is one of the leading reasons for human death worldwide. In cancer research, nanomaterials are evaluated as an encouraging system due to their promising properties, consisting of nanoscale sizes and chemical and physical configurations that can be functionalized for the final application. Although much effort has been extended to efficient cancer research, the biocompatibility and toxicity of nanomaterials remain the main challenges. Cellular reactions are correlated with the physicochemical characteristics of nanomaterials. There are several structural parameters on which nanotoxicological reactions depend, such as size, charge, surface chemistry, and morphology. Notably, understanding the challenges is highly desirable to take full advantage of the benefits provided by nanomaterials. Therefore, this chapter covers the latest biocompatibility and toxicity findings from cancer studies using nanomaterials. Moreover, this chapter demonstrates the experiences learned and challenges faced by a group of leading scientists in this discipline. Also, it covers the physical, chemical, and biological strategies to make nanomaterials more biocompatible and nontoxic.
dc.identifier.citationYaşayan, G., Alarcin, E., Avci-Adali, M., Ipek, T. C., Nejati, O., Özcan-Bülbül, E., ... & Mostafavi, E. (2024). Biocompatibility and toxicity challenges of nanomaterials. In Functionalized Nanomaterials for Cancer Research (pp. 603-631). Academic Press.
dc.identifier.doi10.1016/B978-0-443-15518-5.00019-7
dc.identifier.endpage631
dc.identifier.isbn978-044315518-5, 978-044315519-2
dc.identifier.scopus2-s2.0-85193343497
dc.identifier.startpage603
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6532
dc.institutionauthorNejati , Omid
dc.institutionauthorÖzcan Bülbül, Ece
dc.institutionauthorBal Öztürk, Ayça
dc.institutionauthoridOmid Nejati / 0000-0003-4983-9280
dc.institutionauthoridEce Özcan Bülbül / 0000-0001-7112-923X
dc.institutionauthoridAyça Bal Öztürk / 0000-0002-6502-528X
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofFunctionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices
dc.relation.publicationcategoryKitap - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBiocompatibility
dc.subjectCancer Research
dc.subjectNanomaterial
dc.subjectToxicity
dc.titleBiocompatibility and toxicity challenges of nanomaterials
dc.typeBook Chapter

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