Evaluation of serum adipocytokine and interleukin-18 levels in patients with epilepsy

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dc.contributor.authorKılınç, Derya
dc.contributor.authorJafar, Vugar
dc.contributor.authorAyan, Orhan
dc.contributor.authorÇevik, Mehmet Uğur
dc.contributor.authorAslanhan, Hamza
dc.contributor.authorDündar, Ahmet
dc.contributor.authorYılmaz, Ahmet
dc.date.accessioned2024-05-19T14:23:34Z
dc.date.available2024-05-19T14:23:34Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractObjective: Epilepsy is a neurological disease characterized by recurrent seizures. The underlying pathophysiological mechanisms in epilepsy are not fully known. Our aim is to investigate the relationship between serum adipocytokine and interleukin (IL)-18 levels in epilepsy patients receiving and not receiving antiepileptic therapy. Method: Our study was established as three groups. I: Epilepsy patients receiving antiepileptic therapy (n=30), II: Newly diagnosed epilepsy patients (n=30) and III: Control group (n=30). Serum adipocytokine and IL-18 levels were measured by enzyme-linked immunoassorbent assay method. Results: It was determined that serum adipocytokine and IL-18 levels were increased in epilepsy patients who received topiramate treatment and did not receive antiepileptic therapy compared to the control group. Serum glucose, total protein, cholesterol and albumin concentrations of patients who received antiepileptic treatment were decreased compared to the control group (p0.05). It was found that the body mass index (BMI) ratio of epilepsy patients who received antiepileptic treatment decreased and was significant compared to the control group and the group that did not receive treatment (pen_US
dc.identifier.doi10.17944/interdiscip.1285784
dc.identifier.endpage24en_US
dc.identifier.issn2980-1915
dc.identifier.issue48en_US
dc.identifier.startpage18en_US
dc.identifier.trdizinid1180625en_US
dc.identifier.urihttps://doi.org/10.17944/interdiscip.1285784
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1180625
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4034
dc.identifier.volume14en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofInterdisciplinary medical journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.titleEvaluation of serum adipocytokine and interleukin-18 levels in patients with epilepsyen_US
dc.typeArticleen_US

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