Abnormal flotation of separator gel in blood test tubes in the hemodialysis patients

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dc.authoridMeltem Demir / 0000-0002-0836-8585en_US
dc.authoridMehmet Sarıer / 0000-0002-8656-7416en_US
dc.authorscopusidMehmet Sarıer / 57193698943
dc.authorscopusidMeltem Demir / 56689396100
dc.authorwosidMehmet Sarıer / B-8589-2018
dc.authorwosidMeltem Demir / AAS-2350-2020
dc.contributor.authorDemir, Meltem
dc.contributor.authorÖzdem, Sebahat
dc.contributor.authorSarıer, Mehmet
dc.date.accessioned2020-12-08T08:28:33Z
dc.date.available2020-12-08T08:28:33Z
dc.date.issued2019en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: Serum-separating tubes (SST) are used in medical clinical chemistry tests requiring blood serum. Blood density is mainly dependent on the total protein concentration. Aim of this study to investigate, whether high protein content due to dehydration during hemodialysis can cause laboratory error with the abnormal flotation in blood tubes. Methods: After examining post hemodialysis (HD) blood samples of three cases with ESRD we investigated the effect of adding bovine albumin to the test tubes to determine whether an increment in protein concentration result in abnormal flotation of separator gel in blood samples obtained from healthy volunteers. Results: Serum total protein levels were markedly increased in blood samples of all 3 cases. In tests using blood samples from healthy volunteers supplemented with bovine albumin to increase the protein load, the test tubes having an albumin concentration greater than 16 g/dl displayed an abnormal flotation of separator gel similar to those we observed in post-HD samples from our cases. Conclusion: Increased protein load, probably caused by Intradialytic hypotension due to dehydration, induces the observed abnormal flotation of separator gel in serum tubes in these cases. Our findings emphasize the importance of visual control of serum tubes to prevent abnormal flotation in blood samples.en_US
dc.identifier.citationDEMİR M,ÖZDEM S,SARIER M (2019). Abnormal Flotation of Separator Gel in Blood Test Tubes in the Hemodialysis Patients. Eurasian Journal of Medical Investigation, 3(4), 280 - 284. Doi: 10.14744/ejmi.2019.82037en_US
dc.identifier.doi10.14744/ejmi.2019.82037en_US
dc.identifier.endpage284en_US
dc.identifier.issn2602-3164en_US
dc.identifier.issn2602-3164en_US
dc.identifier.issue4en_US
dc.identifier.startpage280en_US
dc.identifier.trdizinid383596en_US
dc.identifier.urihttps://doi.org/10.14744/ejmi.2019.82037
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1267
dc.identifier.volume3en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorDemir, Meltem
dc.institutionauthorSarıer, Mehmet
dc.language.isoenen_US
dc.relation.ispartofEurasian Journal of Medical Investigationen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAbnormal Flotationen_US
dc.subjectHemodialysisen_US
dc.subjectSepartor Gelen_US
dc.subjectTest Tubesen_US
dc.titleAbnormal flotation of separator gel in blood test tubes in the hemodialysis patientsen_US
dc.typeArticleen_US

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