Modulation of YAP1 expression and other related signaling pathways in HepG2 cells by extracellular matrix, contact inhibition and cell density

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dc.authoridAyça Karagöz Köroğlu / 0000-0002-2532-8091en_US
dc.authorscopusidAyça Karagöz Köroğlu / 57217538082
dc.authorwosidAyça Karagöz Köroğlu / DXI-1614-2022
dc.contributor.authorAktaş, Ranan, Sr.
dc.contributor.authorAkbulut, Zeynep
dc.contributor.authorMaraş, Hatice, Jr.
dc.contributor.authorÇakıl, Yaprak Dönmez
dc.contributor.authorKayalı, Damla
dc.contributor.authorKaragöz Köroğlu, Ayça
dc.contributor.authorSitar, Mustafa Erinç
dc.contributor.authorKısakol, Batuhan
dc.contributor.authorBaysan, Mehmet
dc.date.accessioned2020-11-06T08:50:12Z
dc.date.available2020-11-06T08:50:12Z
dc.date.issued2020en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Hippo-YAP pathway is a key modulator in liver development, egeneration and the metabolism . Cell density, cell contact, the actin cytoskeleton, and extracellular matrix (ECM) composition have been shown to be involved in regulation of this pathway . The intervention of this pathway in hepatocellular carcinoma remains a central focus . The study aimed to examine how YAP1 integrate mechanical cues with the response to signal transduction pathways and to multiple aspects of cell behavior, proliferation, protein/lipid secretion, apoptosis/necrosis, adhesion, and stemness .en_US
dc.identifier.endpage239Aen_US
dc.identifier.issn0270-9139en_US
dc.identifier.issn1527-3350en_US
dc.identifier.startpage239Aen_US
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1177
dc.identifier.volume72en_US
dc.identifier.wosWOS:000574027000377en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorKaragöz Köroğlu, Ayça
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofHEPATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleModulation of YAP1 expression and other related signaling pathways in HepG2 cells by extracellular matrix, contact inhibition and cell densityen_US
dc.typeArticleen_US

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