Tackling chronic wound healing using nanomaterials: advancements, challenges, and future perspectives

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dc.authoridYaşayan, Gökçen/0000-0002-5299-2924
dc.authoridMostafavi, Ebrahim/0000-0003-3958-5002
dc.authoridZarrabi, Ali/0000-0003-0391-1769
dc.authoridZarepour, Atefeh/0000-0002-0347-5840
dc.authoridKarasu, Çimen/0000-0002-0954-8465
dc.authoridBAL OZTURK, AYCA/0000-0002-6502-528X
dc.authorwosidYaşayan, Gökçen/E-4506-2013
dc.authorwosidMostafavi, Ebrahim/X-3674-2019
dc.authorwosidZarrabi, Ali/U-2602-2019
dc.authorwosidZarepour, Atefeh/AAH-9225-2020
dc.authorwosidKarasu, Çimen/JVZ-4637-2024
dc.authorwosidBAL OZTURK, AYCA/M-4472-2018
dc.contributor.authorYasayan, Gokcen
dc.contributor.authorNejati, Omid
dc.contributor.authorCeylan, Asli F.
dc.contributor.authorKarasu, Cimen
dc.contributor.authorUgur, Pelin Kelicen
dc.contributor.authorBal-Ozturk, Ayca
dc.contributor.authorZarepour, Atefeh
dc.date.accessioned2024-05-19T14:40:06Z
dc.date.available2024-05-19T14:40:06Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractChronic wounds are known as one of the biggest health challenges, especially in the case of diabetes patients, which annually engages millions of patients, and its management imposes an exorbitant economic cost on so-cieties worldwide. Therefore, there is an unmet need to find novel therapeutic methods with lower costs and higher efficiency. In recent years, a wide range of nanomaterials (NMs) has been utilized and shown promising results in treating different types of chronic wounds via playing a vital role as carriers for therapeutic agents or directly act as the therapeutic compound. NMs could affect different phases of the healing process, from he-mostasis to remodeling, via influencing various intracellular factors. Towards this, the current review aims to provide the most recent research progress and prospect on the application of different NMs in chronic wound healing, particularly focusing on their effects on intracellular factors. The chronic wounds and intracellular pathways involved in this process are elaborated, and several NMs-based therapeutic agents used for chronic wound healing are described. The potential pitfalls and challenges of utilizing NMs in chronic wound healing are covered, and future perspectives toward more successful translational applications are presented.en_US
dc.identifier.doi10.1016/j.apmt.2023.101829
dc.identifier.issn2352-9407
dc.identifier.scopus2-s2.0-85154056247en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org10.1016/j.apmt.2023.101829
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4905
dc.identifier.volume32en_US
dc.identifier.wosWOS:000993782400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofApplied Materials Todayen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectChronic Woundsen_US
dc.subjectIntracellular Mechanismen_US
dc.subjectNanomaterialsen_US
dc.subjectScaffoldsen_US
dc.titleTackling chronic wound healing using nanomaterials: advancements, challenges, and future perspectivesen_US
dc.typeArticleen_US

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