Thrombolysis in myocardial infarction risk index predicts one-year mortality in patients with heart failure: an analysis of the SELFIE-TR study

dc.authoridTolga Sinan Güvenç / 0000-0002-6738-266Xen_US
dc.authorscopusidTolga Sinan Güvenç / 6602421975en_US
dc.authorwosidTolga Sinan Güvenç / JQN-5460-2023
dc.contributor.authorGüvenç, Rengin Çetin
dc.contributor.authorGüvenç, Tolga Sinan
dc.contributor.authorUral, Dilek
dc.contributor.authorCavusoglu, Yuksel
dc.contributor.authorYilmaz, Mehmet Birhan
dc.date.accessioned2022-11-11T08:10:58Z
dc.date.available2022-11-11T08:10:58Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Predicting outcomes is an essential part of evaluation in patients with heart failure (HF). While there are multiple individual laboratory and imaging variables, as well as risk scores available for this purpose, they are seldom useful during the initial evaluation. In this analysis, we aimed to understand predictive usefulness of Thrombosis in Myocardial Infarction Risk Index (TIMI-RI), a simple index that is calculated at bedside using three commonly available variables, using data from a multicenter HF registry. Subjects and Methods: A total of 728 patients from 23 centers were included to this analysis. Data on hospitalizations and mortality were collected by direct interviews, phone calls and electronic databases. TIMI-RI was calculated as defined before. Patients were divided into three equal tertiles to perform analyses. Results: Rehospitalization for HF was significantly higher in patients within the 3rd tertile, and 33.5% of patients within the 3rd tertile were dead within one-year follow up as compared to 14.5% of patients within the 1st tertile and 15.6% patients within the 2nd tertile (p<0.001, log-rank p<0.001 for pairwise comparisons on survival analysis). A TIMI-RI higher than 33 had a negative predictive value of 84.8% and a positive predictive value of 33.8% for prediction of one-year mortality. This predictive usefulness was independent of other demographic, examination and clinical variables (OR:1.74, 95%CI:1.05-2.86, p=0.036). Conclusion: TIMI-RI is a simple index that predicts one-year mortality in patients with HF, and it could be useful for rapid evaluation and triage of HF patients at the time of initial contact.en_US
dc.identifier.citationGüvenç, R. Ç., Güvenç, T. S., Ural, D., Çavuşoğlu, Y., & Yılmaz, M. B. (2022). Thrombolysis in Myocardial Infarction Risk Index Predicts One-Year Mortality in Patients with Heart Failure: An Analysis of the SELFIE-TR Study. Medical Principles and Practice.en_US
dc.identifier.doi10.1159/000527214en_US
dc.identifier.scopus2-s2.0-85145641581en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1159/000527214
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3323
dc.identifier.wosWOS:000862157800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorGüvenç, Tolga Sinan
dc.language.isoenen_US
dc.publisherKARGERen_US
dc.relation.ispartofMEDICAL PRINCIPLES AND PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHeart Failureen_US
dc.subjectMortalityen_US
dc.subjectThrombolysis in Myocardial Infarction Risk Indexen_US
dc.titleThrombolysis in myocardial infarction risk index predicts one-year mortality in patients with heart failure: an analysis of the SELFIE-TR studyen_US
dc.typeArticleen_US

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