Effect of preoperative serum transthyretin levels on postoperative clinical results and morbidity in patients undergoing spinal surgery

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dc.authoridBora Gürer / 0000-0003-1500-6184en_US
dc.authorscopusidBora Gürer / 36448801100en_US
dc.authorwosidBora Gürer / K-1177-2012
dc.contributor.authorKertmen Hayri
dc.date.accessioned2022-01-28T08:18:51Z
dc.date.available2022-01-28T08:18:51Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction: This study aims to investigate the effects of preoperative serum transthyretin (TTR) levels on surgical success, pain scores, and postoperative morbidity. Methods: Note that, in our clinic, 188 patients who were operated for spinal pathologies between June 2010 and January 2011 were included in this study. Blood samples were drawn from all patients on the morning of surgery, and then, serum TTR measurements were made. Demographic data of all patients were collected, and then their preoperative and postoperative neurological examinations, Karnofsky scores, Visual Analog Scale (VAS) scores, Oswestry disability index (ODI) scores, postoperative infection and wound healing status, hospital stay, and morbidity levels were recorded, and TTR levels were compared. Results: When preoperative TTR level of patients was low, their Karnofsky scores decreased, ODI scores increased, the early postoperative VAS and late postoperative VAS values increased, and the length of hospital stay was increased. Moreover, in patients with low TTR levels, postoperative Karnofsky scores were lower, postoperative ODI levels were higher, postoperative early and late VAS scores were higher, hospital stays were longer, peroperative complication rates were higher, wound infection rates were higher, the delay in wound site healing was higher, and the morbidity rate was higher. Conclusion: Consequently, preoperative low TTR levels have been reported to be an effective parameter that can be used to predict surgical results, wound infection and wound site healing status, perioperative complications, and morbidity in spinal surgery.en_US
dc.identifier.citationGürer B, Kertmen H. Effect of Preoperative Serum Transthyretin Levels on Postoperative Clinical Results and Morbidity in Patients Undergoing Spinal Surgery. Asian J Neurosurg. 2021 Dec 18;16(4):811-816.en_US
dc.identifier.doi10.4103/ajns.ajns_228_21en_US
dc.identifier.endpage816en_US
dc.identifier.issue4en_US
dc.identifier.pmid35071082en_US
dc.identifier.startpage811en_US
dc.identifier.urihttps://doi.org/10.4103/ajns.ajns_228_21
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2433
dc.identifier.volume16en_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGürer, Bora
dc.language.isoenen_US
dc.publisherMedknowen_US
dc.relation.ispartofAsian J Neurosurgen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSpinal Surgeryen_US
dc.subjectSurgical Resultsen_US
dc.subjectTransthyretinen_US
dc.titleEffect of preoperative serum transthyretin levels on postoperative clinical results and morbidity in patients undergoing spinal surgeryen_US
dc.typeArticleen_US

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