Impaired memory by hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic fields is ameliorated by thymoquinone

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dc.authoridHuri Bulut / 0000-0003-2706-9625en_US
dc.authorscopusidHuri Bulut / 57185264300en_US
dc.authorwosidHuri Bulut / AAM-1432-2020
dc.contributor.authorÜstünova, S.
dc.contributor.authorKılıç, A.
dc.contributor.authorBulut, H.
dc.contributor.authorGürel-Gürevin, E.
dc.contributor.authorEriş, A.H.
dc.contributor.authorMeral, I.
dc.date.accessioned2022-04-06T05:41:15Z
dc.date.available2022-04-06T05:41:15Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractThe protective effects of thymoquinone on learning and memory abilities and on hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic field radiation at s strength of 6.0 ± 0.5 V/m for 1 h on each of 15 days was studied. Thymoquinone-treatment (10 mg/kg/day) of radiation-exposed rats resulted in better performance than that of radiation-exposed rats not receiving thymoquinone. Electromagnetic field-exposure led to increased hippocampal superoxide dismutase, glutathione peroxidase, and malondialdehyde levels and to lowered brain-derived neurotrophic factor level; thymoquinone treatment ameliorated all four parameters. Also, in the electromagnetic field-exposed group, N-methyl-D-aspartate receptor expression decreased, and gamma-aminobutyric-acid alpha receptor expression increased, which was reversed by thymoquinone treatment. In conclusion, treatment with the thymoquinone ameliorated the impact of the exposure to EMF and provided a hint on the mechanism involving oxidative stress. © 2022 Informa UK Limited, trading as Taylor & Francis Group.en_US
dc.identifier.citationERİŞ, A. H., ÜSTÜNOVA, S., KILIÇ, A., Bulut, H., Gurel-Gurevin, E., & MERAL, İ. (2022). Impaired memory by hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic fields is ameliorated by thymoquinone.en_US
dc.identifier.doi10.1080/02772248.2022.2051509en_US
dc.identifier.issn0277-2248en_US
dc.identifier.scopus2-s2.0-85126664646en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1080/02772248.2022.2051509
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2610
dc.identifier.wosWOS:000769251600001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBulut, Huri
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofToxicological and Environmental Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject900 MHz EMFen_US
dc.subjectCognitive Functionsen_US
dc.subjectHippocampusen_US
dc.subjectOxidative Stressen_US
dc.subjectThymoquinoneen_US
dc.titleImpaired memory by hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic fields is ameliorated by thymoquinoneen_US
dc.typeArticleen_US

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