The first serological detection of West Nile virus infection among residents living in northern Turkey

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dc.authoridYAZICI, Zafer/0000-0002-2806-7878
dc.authoridÖZAN, Emre/0000-0001-9872-8152
dc.authoridElhag, Ahmed Eisa/0000-0002-0738-1825
dc.authoridTAMER, Cüneyt/0000-0003-3240-8425
dc.authoridMesquita, Joao/0000-0001-8769-8103
dc.authoridALBAYRAK, Harun/0000-0002-4468-2790
dc.authorwosidYAZICI, Zafer/AAV-5880-2021
dc.authorwosidÖZAN, Emre/AAB-8896-2020
dc.authorwosidElhag, Ahmed Eisa/AAU-7483-2020
dc.authorwosidTAMER, Cüneyt/AFH-9368-2022
dc.authorwosidMesquita, Joao/B-6960-2016
dc.contributor.authorTaskin, Mehmet Hakan
dc.contributor.authorTamer, Cuneyt
dc.contributor.authorMuftuoglu, Bahadir
dc.contributor.authorOzan, Emre
dc.contributor.authorKilic, Suleyman Sirri
dc.contributor.authorAkkoyunlu, Gokce Kubra
dc.contributor.authorKurucay, Hanne Nur
dc.date.accessioned2024-05-19T14:41:12Z
dc.date.available2024-05-19T14:41:12Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBackground & objectives: West Nile virus (WNV) is transmitted by a mosquito-borne virus whose natural reservoir is birds. Humans and horses are considered accidental hosts. Even if the vast majority of WNV infections in humans have asymptomatic or mild disease settings, serious neurological disorders with lethal outcomes can also be observed in around 1% of the cases. We aimed to serologically investigate the presence of WNV in humans living in Black sea of Turkey, and to obtain epidemiological data that will contribute to the implementation of public health policies to control and prevent potentially other life-threatening arboviral infections.Methods: In the current study, a total of 416 human sera were collected from native patients of Samsun and its boroughs attending Samsun Training and Research Hospital; these sera were tested for WNV with pooling method, using anti-IgM and IgG ELISA commercial kits. All pools that were found positive for both IgM and IgG were individually retested for the detection of positive WNV sera. After that, all positive samples were tested using real-time PCR to detect the presence of WNV-RNA particles. Results: Total seropositivity rates of WNV in terms of IgM and IgG were found as 0.96% and 0.72%, respectively. No presence of WNV-RNA could be detected in positive samples.Interpretation & conclusion: According to the data, further studies should be conducted to better understand the epidemiological dynamics of WNV in Turkey. It is recommended that other antigenically related flaviviruses which can give cross-reaction with WNV should also be investigated.en_US
dc.identifier.doi10.4103/0972-9062.364755
dc.identifier.endpage105en_US
dc.identifier.issn0972-9062
dc.identifier.issue1en_US
dc.identifier.pmid37026226en_US
dc.identifier.startpage101en_US
dc.identifier.urihttps://doi.org10.4103/0972-9062.364755
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5078
dc.identifier.volume60en_US
dc.identifier.wosWOS:000982088400013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofJournal of Vector Borne Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectElisaen_US
dc.subjectNative Patientsen_US
dc.subjectNorth Turkeyen_US
dc.subjectSeroprevalenceen_US
dc.subjectWest Nile Virusen_US
dc.titleThe first serological detection of West Nile virus infection among residents living in northern Turkeyen_US
dc.typeArticleen_US

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