Gebelerde bakteriyel vajinozisin oral ve oral + vajinal tedavisinin gebelik komplikasyonları üzerine etkisi
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Dosyalar
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bakteriyel Vaginosis (BV), anormal vajinal flora ile karakterize, iyi bilinen bir hastalıktır. Preterm doğum için önemli bir risk faktörüdür. Amacımız BV'si olan gebelerde preterm doğum riskini azaltmada hangi tedavi seçeneğinin daha iyi olduğunu bulmaktı.Materyal ve Metod: Bu prospektif çalışmada 24-28. Gebelik haftalarında antenatal polikliniğimize vajinal akıntı şikâyeti ile başvuran toplam 60 gebe kadını değerlendirdik. 60 hastanın 25'i nitroimidazol + mikonazol nitrat intravajinal, diğer hastalara ise oral imidazol + vajinal mikonazol ile tedavi edildi.Bulgular: Tedavi seçenekleri arasında servikal uzunluk, preterm doğum riski ve PPROM arasında anlamlı bir farklılık bulunmadığını saptadık.Sonuç: Gebeliğin erken dönemlerinde saptanan BV'nin tedavisi, gebelik sonuclarını olumlu yönde etkileyebilir. Nitroimidazolidin oral veya vajinal kullanımı BV'nin tedavisinde etkilidir. Vaginal veya oral kullanım ile elde edilen fayda benzerdir
Objective: Bacterial Vaginosis (BV) is a well-known disease which is characterized with abnormal vaginal flora. It is an important risk factor for preterm delivery in pregnancy. Our aim was to find out which treatment option was better in reducing the risks of preterm delivery in pregnant women with BV.Materials and Methods: This prospective study includes a total of sixty singleton pregnant women with complaining of vaginal discharge who were admitted to the our obstetrics outpatient clinic at 24 to 28 weeks of gestation. Out of 60 patients, 25 of them were treated with nitroimidazole + miconazole nitrate intravaginaly and the rest was treated with oral imidazole + vaginal miconazole. Results: There was no statistically significant differences in cure rates for bacterial vaginosis in terms of treatment with oral vs oral plus vaginal treatment groups (%82.8, %77.1 respectively, p=0.258 ). We found that there were no significant differences in cervical length, risk of preterm delivery, and PPROM between treatment options. When BV treated with vaginally, 4 out of 25 (%16) pregnant woman had preterm delivery; in the oral+vaginally treated group 8 out of 35 (%22,9) pregnant had preterm delivery (p Conclusion: Treatment of the BV detected early in pregnancy may have a positive impact on the outcome of the pregnancy. Oral or vaginal use of nitroimidazolide is effective in the treatment of BV
Objective: Bacterial Vaginosis (BV) is a well-known disease which is characterized with abnormal vaginal flora. It is an important risk factor for preterm delivery in pregnancy. Our aim was to find out which treatment option was better in reducing the risks of preterm delivery in pregnant women with BV.Materials and Methods: This prospective study includes a total of sixty singleton pregnant women with complaining of vaginal discharge who were admitted to the our obstetrics outpatient clinic at 24 to 28 weeks of gestation. Out of 60 patients, 25 of them were treated with nitroimidazole + miconazole nitrate intravaginaly and the rest was treated with oral imidazole + vaginal miconazole. Results: There was no statistically significant differences in cure rates for bacterial vaginosis in terms of treatment with oral vs oral plus vaginal treatment groups (%82.8, %77.1 respectively, p=0.258 ). We found that there were no significant differences in cervical length, risk of preterm delivery, and PPROM between treatment options. When BV treated with vaginally, 4 out of 25 (%16) pregnant woman had preterm delivery; in the oral+vaginally treated group 8 out of 35 (%22,9) pregnant had preterm delivery (p Conclusion: Treatment of the BV detected early in pregnancy may have a positive impact on the outcome of the pregnancy. Oral or vaginal use of nitroimidazolide is effective in the treatment of BV
Açıklama
Anahtar Kelimeler
Bakteriyel Vajinozis, Mikonazol, Nitroimidazol, Bacterial Vaginosis, Micozanole, Nitroimidazole
Kaynak
Ege Klinikleri Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
55
Sayı
2
Künye
BAŞBUĞ A,ÇALIŞKAN Ş,KAYA A. E,BENDER R. A,AKAR B,ÖZCAN C,ÇALIŞKAN E (2017). Gebelerde Bakteriyel Vajinozisin Oral ve Oral + Vajinal Tedavisinin Gebelik Komplikasyonları Üzerine Etkisi. Ege Klinikleri Tıp Dergisi, 55(2), 61 - 64.
