Diabetic microvascular complications and proposed interventions and approaches of management for patient care

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dc.authoridAnmar Al-Taie / 0000-0002-2183-6830
dc.authorscopusidAnmar Al-Taie / 57221579036
dc.authorwosidAnmar Al-Taie / I-8549-2019
dc.contributor.authorAl-Taie, Anmar
dc.contributor.authorElseidy, Assem Sabbah
dc.contributor.authorVictoria, Arueyingho Oritsetimeyin
dc.contributor.authorHafeez, Abdul
dc.contributor.authorAhmad, Shmmon
dc.date.accessioned2022-01-03T05:41:19Z
dc.date.available2022-01-03T05:41:19Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümüen_US
dc.description.abstractPatients with diabetes mellitus are more likely to suffer microvascular complications, such as diabetic retinopathy, diabetic nephropathy, and diabetic neuropathy, which, if undiagnosed or untreated, may have a debilitating effect on patients' quality of life and pose a substantial financial strain on health-care providers. Glycemic regulation and diabetes length are the most powerful risk factors; nevertheless, other modifiable risk factors including hypertension, hyperlipidemia, and smoking, as well as unmodifiable risk factors, including age at onset of diabetes and genetic factors can all play a role. In addition to the involvement of potential risk factors, several links have been discovered between diabetic microvascular complications and one another, which seems to be significant associations for the development of these different microvascular complications. However, in order to help mitigate morbidity and mortality, considering the initiation and progression of all three complications as interconnected must be identified and managed at an early stage. Therefore, a variety of approaches to developing therapies to mitigate the negative effects of these complications are currently being studied in clinical trials which may contribute to potential long-term benefits in the management of different diabetic microvascular complications. This literature review summarizes the cellular and molecular pathways that lead to diabetic microvascular pathologies with emphasis on the clinical benefits of a variety of therapeutic approaches and insights into simple, comprehensive therapeutic interventions for clinical practice which could be optimal to reduce the risk and severity of different diabetic microvascular complications.en_US
dc.identifier.citationAl-Taie, A., Elseidy, A. S., Victoria, A. O., Hafeez, A., & Ahmad, S. (2021). Diabetic microvascular complications and proposed interventions and approaches of management for patient care. Biomedical and Biotechnology Research Journal (BBRJ), 5(4), 380.en_US
dc.identifier.doi10.4103/bbrj.bbrj_153_21en_US
dc.identifier.endpage388en_US
dc.identifier.issn2588-9834en_US
dc.identifier.issn2588-9842en_US
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85122033030en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage380en_US
dc.identifier.urihttps://doi.org/10.4103/bbrj.bbrj_153_21
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2377
dc.identifier.volume5en_US
dc.identifier.wosWOS:000732754300005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorAl-Taie, Anmar
dc.language.isoenen_US
dc.publisherWOLTERS KLUWER MEDKNOW PUBLICATIONSen_US
dc.relation.ispartofBIOMEDICAL AND BIOTECHNOLOGY RESEARCH JOURNALen_US
dc.relation.publicationcategoryDiÄŸeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiabetic Nephropathyen_US
dc.subjectDiabetic Neuropathyen_US
dc.subjectDiabetic Retinopathyen_US
dc.subjectMicrovascular Complicationsen_US
dc.subjectSupplementsen_US
dc.titleDiabetic microvascular complications and proposed interventions and approaches of management for patient careen_US
dc.typeReview Articleen_US

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