Carotid artery stenting without embolic protection: A randomized multicenter trial (the CASWEP trial)

Basit Öğe Kaydı
dc.authoridMüslüm Şahin / 0000-0003-4976-6720en_US
dc.authorscopusidMüslüm Şahin / 41862126900en_US
dc.authorwosidMüslüm Şahin / DNT-9358-2022
dc.contributor.authorGörgülü, Şevket
dc.contributor.authorŞahin, Müslüm
dc.contributor.authorNorgaz, Niyazi Tuğrul
dc.contributor.authorPala, Selçuk
dc.contributor.authorYalçın, Ahmet Arif
dc.contributor.authorSipahi, İlke
dc.contributor.authorSarı, Münevver
dc.date.accessioned2022-06-07T08:14:13Z
dc.date.available2022-06-07T08:14:13Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Carotid artery stenting (CAS) with a carotid protection device (CPD) has become the standard practice in patients with severe carotid stenosis and high surgical risk. However, the clinical efficacy and safety of CPDs are still controversial issues. We aimed to compare the clinical outcomes of the CAS without CPD with CAS combined with CPD. Methods: This is a multicenter randomized prospective study registered with http://clinicaltrials.gov (NCT02781181). After the exclusion, 279 patients were enrolled (139 patients in the CAS with CPD group and 140 patients in the CAS without CPD group). The primary outcome was a combination of peri-procedural in-hospital transient ischemic attack (TIA), ipsilateral stroke, or death. The secondary outcome was new ischemic brain lesions on post-procedural diffusion-weighted magnetic resonance imaging (DW-MRI). Results: Two patients died in CAS without CPD group, one patient died in CAS with CPD group. TIA was only seen in patients who underwent CAS under protection (n = 5). The combined primary outcome of TIA, ipsilateral stroke, and death rate was not different between groups (5.7% vs. 2.8%; p = 0.254). New defects were noted on the post-procedural DW-MRI in 28% of patients in the CPD group and 27% of patients in the no CPD group (p = 0.881). Conclusions: This study suggests that CAS without CPD is not associated with higher rates of peri-procedural TIA, stroke, and death or new ischemic brain lesions on post-procedural DW-MRI compared to CAS with CPD in selected symptomatic and asymptomatic patients with significant carotid artery stenosis provided that there is no visible thrombus. © The Author(s) 2022.en_US
dc.identifier.citationGorgulu, S., Sahin, M., Norgaz, N. T., Pala, S., Sarı, M., Yalcin, A. A., & Sipahi, I. (2022). Carotid artery stenting without embolic protection: A randomized multicenter trial (the CASWEP trial). Interventional Neuroradiology, doi:10.1177/15910199221094388en_US
dc.identifier.doi10.1177/15910199221094388en_US
dc.identifier.issn1591-0199en_US
dc.identifier.scopus2-s2.0-85129872195en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1177/15910199221094388
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2822
dc.identifier.wosWOS:000798425600001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorŞahin, Müslüm
dc.language.isoenen_US
dc.publisherSAGE Publications Inc.en_US
dc.relation.ispartofInterventional Neuroradiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarotid Artery Stentingen_US
dc.subjectEmbolic Complicationen_US
dc.subjectProtection Deviceen_US
dc.titleCarotid artery stenting without embolic protection: A randomized multicenter trial (the CASWEP trial)en_US
dc.typeArticleen_US

Dosyalar

Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu