The formulation and microstructural, rheological, and textural characterization of salep-xanthan gum-based liposomal gels

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dc.authoridZeynep Hazal Tekin Çakmak / 0000-0002-3369-3128en_US
dc.authorwosidZeynep Hazal Tekin Çakmak / W-1211-2019en_US
dc.contributor.authorSaroğlu, Öznur
dc.contributor.authorKaradağ, Ayşe
dc.contributor.authorÇakmak, Zeynep Hazal Tekin
dc.contributor.authorKarasu, Salih
dc.date.accessioned2022-11-14T11:30:47Z
dc.date.available2022-11-14T11:30:47Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesien_US
dc.description.abstractThis study aimed to determine the morphological, Rheological, and textural characterization of xanthan gum-salep liposomal gels. The particle size of liposomes (94.21 +/- 0.57 nm) was increased in liposomal gels, and it was highest (116.83 +/- 1.97 nm) in the K1S3 formulation. The surface charge of liposomes was - 37.40 +/- 3.05 mV, and it was significantly decreased by the addition of polymers, changing between - 28.53 and - 30.63 mV. SEM analysis showed that the hydrogel and liposomal gels did not have any aggregation and had a bird net porous morphology and uniform distribution of liposomes. FTIR analysis revealed an interaction between xanthan gum-salep and lecithin. TEM analysis showed spherical structures of liposomes with no obvious aggregation and their size determined by TEM complied with the results taken by DLS analysis. The rheological properties of hydrogels and liposomal gels were characterized by steady shear, frequency, and temperature sweep test, and 3-ITT analysis. All hydrogels and liposomal gels samples showed non-Newtonian, solid-like, and recoverable characters, which increased with an increase in salep concentration in gel formulation. The textural properties of the both hydrogels and liposomal gels were significantly affected by salep-xanthan gum concentration in gels. The results of this study suggested that xanthan gum-salep liposomal gels with strong mechanical properties could be produced by increasing the salep ratio in gel formulation.en_US
dc.identifier.citationSaroglu, O., Karadag, A., Cakmak, Z. H. T., & Karasu, S. (2022). The formulation and microstructural, rheological, and textural characterization of salep-xanthan gum-based liposomal gels. Polymer Bulletin, 1-22.en_US
dc.identifier.doi10.1007/s00289-022-04546-yen_US
dc.identifier.issn0170-0839en_US
dc.identifier.issn1436-2449en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s00289-022-04546-y
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3382
dc.identifier.wosWOS:000877401000002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÇakmak, Zeynep Hazal Tekin
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofPOLYMER BULLETINen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLiposomal Gelsen_US
dc.subjectRheologyen_US
dc.subjectTEMen_US
dc.titleThe formulation and microstructural, rheological, and textural characterization of salep-xanthan gum-based liposomal gelsen_US
dc.typeArticleen_US

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