Stem cell based therapy option in COVID-19: is it really promising?

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dc.authoridDuygu Koyuncu Irmak / 0000-0002-3277-5535en_US
dc.authoridHakan Darıcı / 0000-0001-9393-554Xen_US
dc.authoridErdal Karaöz / 0000-0002-9992-833X
dc.authorscopusidDuygu Koyuncu Irmak / 57219539042
dc.authorscopusidHakan Darıcı / 22333489600
dc.authorscopusidErdal Karaöz / 7003448087
dc.authorwosidHakan Darıcı / AAG-4316-2019
dc.authorwosidErdal Karaöz / AAO-1470-2020
dc.authorwosidDuygu Koyuncu Irmak / CWZ-0318-2022
dc.contributor.authorKoyuncu Irmak, Duygu
dc.contributor.authorDarıcı, Hakan
dc.contributor.authorKaraöz, Erdal
dc.date.accessioned2020-10-15T07:19:31Z
dc.date.available2020-10-15T07:19:31Z
dc.date.issued2020en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractThe COVID-19 patients were first detected in China, in December 2019, then the novel virus with associated pneumonia and other diseases spread quickly to worldwide becoming a serious public health intimidation. Despite all the efforts, the pharmacological agents used for controlling or treating the disease, especially respiratory problems, have not been accomplished so far. Among various treatment options, mesenchymal stem cell-based cellular therapies are being investigated, because of their regeneration ability and multipotency along with other features like immunomodulation, antifibrosis and anti- inflammatory effects. This paper intends to analyze the current clinical trials on stem cell treatment of novel virus, searching and reviewing the available information and the International Clinical Trials Registry Platform (ICTRP) of World Health Organization (WHO). We concluded that the stem cell treatment of COVID-19 is found promising with pilot studies' results, but still in the early development phase. There is an urgent need for large-scale investigations to confirm and validate the safety and efficacy profile of these therapies with reliable scientific evidence.en_US
dc.identifier.citationIrmak, D. K., Darıcı, H., & Karaöz, E. (2020). Stem Cell Based Therapy Option in COVID-19: Is It Really Promising?. Aging and disease, 11(5), 1174.en_US
dc.identifier.doi10.14336/AD.2020.0608en_US
dc.identifier.endpage1190en_US
dc.identifier.issn2152-5250en_US
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85093703385en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1174en_US
dc.identifier.urihttps://doi.org/10.14336/AD.2020.0608
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1137
dc.identifier.volume11en_US
dc.identifier.wosWOS:000574428300013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKoyuncu Irmak, Duygu
dc.institutionauthorDarıcı, Hakan
dc.institutionauthorKaraöz, Erdal
dc.language.isoenen_US
dc.publisherINT SOC AGING & DISEASEen_US
dc.relation.ispartofAGING AND DISEASEen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectStem Cellen_US
dc.subjectTreatmenten_US
dc.subjectCOVID-19en_US
dc.subjectClinicalen_US
dc.subjectTrialsen_US
dc.titleStem cell based therapy option in COVID-19: is it really promising?en_US
dc.typeReview Articleen_US

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