History and development of non-coding RNAs

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dc.authoridGizem Çelebi / 0000-0002-4985-3632
dc.authoridElif Karlık / 0000-0003-0669-2725
dc.authoridNermin Gözükırmızı / 0000-0002-7129-3045
dc.authorscopusidGizem Çelebi / 57218821295
dc.authorscopusidElif Karlık / 56926577900
dc.authorscopusidNermin Gözükırmızı / 6701520637
dc.authorwosidGizem Çelebi / HTR-4612-2023
dc.authorwosidNermin Gözükırmızı / M-1419-2013
dc.authorwosidElif Karlık / N-6348-2018
dc.contributor.authorGözükırmızı, Nermin
dc.contributor.authorKarlık, Elif
dc.contributor.authorÇelebi, Gizem
dc.date.accessioned2020-08-30T20:01:34Z
dc.date.available2020-08-30T20:01:34Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümüen_US
dc.description.abstractThe recent approaches including whole-genome and RNA-sequencing (RNA-seq) studies have declared the landscape of transcription in eukaryotes is notably more complicated than had been previously appreciated. Many different non-coding RNAs (ncRNAs), which contain no open reading frame (ORF), in most of higher organisms have been identified by using several approaches such as computational and experimental. While protein-coding genes constitute only a small portion of the eukaryotic genome, recent transcriptomic studies have revealed the widespread occurrence of ncRNAs. ncRNAs are categorized into two groups as housekeeping and regulatory ncRNAs. Housekeeping ncRNAs are constitutively expressed and categorized as ribosomal RNAs (rRNAs), transfer RNAs (tRNAs), small nuclear RNAs (snRNAs), and small nucleolar RNAs (snoRNAs). The regulatory ncRNAs can be classified as short RNAs (<200 nt), - including microRNAs (miRNAs) and small interfering RNAs (siRNAs) - and long ncRNAs (lncRNAs; >200 nt) depending on their length. ncRNAs have significant roles in the regulation of biological events, such as environmental stress response to transcriptional or post-transcriptional levels. After a short historical review on the ncRNAs, we briefly explain their regulatory role in the cell. © 2020 Nova Science Publishers, Inc. All rights reserved.en_US
dc.identifier.citationGozukirmizi, N., Karlik, E., & Celebi, G. (2020). History and development of non-coding RNAs.en_US
dc.identifier.endpage94en_US
dc.identifier.isbn9781536172669; 9781536172652
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage63en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12713/292
dc.indekslendigikaynakScopusen_US
dc.institutionauthorGözükırmızı, Nerminen_US
dc.institutionauthorKarlık, Elifen_US
dc.institutionauthorÇelebi, Gizemen_US
dc.language.isoenen_US
dc.publisherNova Science Publishers, Inc.en_US
dc.relation.ispartofRecent Advances in Plant Scienceen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCircrnasen_US
dc.subjectLncrnasen_US
dc.subjectMirnasen_US
dc.subjectNon-Coding Rnasen_US
dc.subjectSirnasen_US
dc.titleHistory and development of non-coding RNAsen_US
dc.typeBook Chapteren_US

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