Laparoscopic Versus Conventional Open Congenital Duodenal Obstruction Repair: A Systematic Review and Meta-analysis

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dc.authorscopusidMustafa Azizoğlu / 58901683600
dc.authorwosidMustafa Azizoğlu / HKV-3601-2023
dc.contributor.authorAzizoğlu, Mustafa
dc.contributor.authorKamçı, Tahsin Onat
dc.contributor.authorKlyuev, Sergey
dc.contributor.authorEscolino, Maria
dc.contributor.authorKarakaş, Esra
dc.contributor.authorGigena, Cecilia
dc.contributor.authorYüksel, Seçil
dc.contributor.authorBakır, Ayten Ceren
dc.contributor.authorOkur, Mehmet Hanifi
dc.contributor.authorShehata, Sameh
dc.date.accessioned2025-04-18T10:53:21Z
dc.date.available2025-04-18T10:53:21Z
dc.date.issued2025
dc.departmentİstinye Üniversitesi, Lisansüstü Eğitim Enstitüsü, Sağlık Bilimleri, Kök Hücre ve Doku Mühendisliği Programı
dc.description.abstractBackground: We conducted a systematic review and meta-analysis to evaluate the safety and effectiveness of laparoscopic surgery (LS) compared to open surgery (OS) for congenital duodenal obstruction (CDO). Methods: We conducted a literature review to find studies comparing LS and OS in neonates with CDO. A meta-analysis was conducted to systematically compile and compare factors, including surgical duration, time of feeding initiation, hospital length of stay (LOS), and postoperative complications. Results: Eleven studies with 1615 patients (LS: 338, OS: 1277) met inclusion criteria. Operative time was observed to be much shorter in the OS group (I2 = 97%); weighted mean difference (WMD) 60.29; 95% confidence interval (CI): 30.29 to 90.28; p < 0.0001). The LS group had a significantly shorter time to initiate feeding (I2 = 0%; WMD -3.38, 95% CI: −4.35 to −2.41; p < 0.00001), shorter time to full feeding (I2 = 0%; WMD -3.64, 95% CI: −5.06 to −2.22; p < 0.00001), and shorter LOS (I2 = 52%; WMD -3.42, 95% CI: −5.75 to −1.08; p = 0.004). There were no significantly differences in the rates of anastomotic leak (I2 = 24%; OR 0.76, 95% CI: 0.12 to 4.67; p = 0.76), anastomotic stricture (I2 = 0%; OR 1.12, 95% CI: 0.39 to 3.20; p = 0.83), postoperative ileus (I2 = 0%; OR 0.60, 95% CI: 0.21 to 1.74; p = 0.34), and overall complications between the groups (I2 = 59%; OR 0.86, 95% CI: 0.42 to 1.74; p = 0.68). The LS group, however, had a significantly decreased frequency of wound infection (I2 = 0%; OR 0.26, 95% CI: 0.08 to 0.82; p = 0.02). Conclusion: Despite certain limitations in our analysis, the laparoscopic approach was associated with comparable postoperative outcomes. Levels of Evidence: 2a. Type of the Study: Meta analysis. © 2024 Elsevier Inc.
dc.identifier.citationAzizoglu, M., Kamci, T. O., Klyuev, S., Escolino, M., Karakas, E., Gigena, C., ... & Shehata, S. (2024). Laparoscopic versus conventional open congenital duodenal obstruction repair: A systematic review and meta‐analysis. Journal of Pediatric Surgery, 161933.
dc.identifier.doi10.1016/j.jpedsurg.2024.161933
dc.identifier.issn00223468
dc.identifier.issue1
dc.identifier.pmid39358072
dc.identifier.scopus2-s2.0-85205342431
dc.identifier.scopusqualityQ1
dc.identifier.urihttp://dx.doi.org/10.1016/j.jpedsurg.2024.161933
dc.identifier.urihttps://hdl.handle.net/20.500.12713/7225
dc.identifier.volume60
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAzizoğlu, Mustafa
dc.institutionauthoridMustafa Azizoğlu / 0009-0000-3563-1230
dc.language.isoen
dc.publisherW.B. Saunders
dc.relation.ispartofJournal of Pediatric Surgery
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCongenital Duodenal Obstruction
dc.subjectOpen Surgery
dc.subjectLaparoscopic Surgery
dc.titleLaparoscopic Versus Conventional Open Congenital Duodenal Obstruction Repair: A Systematic Review and Meta-analysis
dc.typeOther

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