The effect of uric acid and albumin ratio in undergoing lower extremity endovascular interventions for peripheral arterial disease related contrast induced nephropathy

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dc.authorscopusidAhmet Anıl Şahin / 57200620149
dc.authorwosidAhmet Anıl Şahin / KPW-2212-2024
dc.contributor.authorDemirci, Gökhan
dc.contributor.authorŞahin, Ahmet Anıl
dc.contributor.authorAltunova, Mehmet
dc.contributor.authorAktemur, Tuğba
dc.contributor.authorAtmaca, Sezgin
dc.contributor.authorYalçın, Ahmet Arif
dc.date.accessioned2025-04-18T09:44:45Z
dc.date.available2025-04-18T09:44:45Z
dc.date.issued2024
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, İSÜ Hastaneleri
dc.description.abstractBackground: Among patients undergoing percutaneous vascular intervention, contrast- induced nephropathy (CIN) is associated with increased morbidity and mortality. Serum uric acid/albumin ratio (UAR) has emerged as a new marker associated with poor cardiovascular outcomes. We aimed to evaluate the relationship between UAR and CIN occurrence in patients treated for peripheral artery disease. Methods: Patients underwent percutaneous intervention due to peripheral artery disease were enrolled. The primary endpoint was development of contrast related nephropathy. Patients were divided into 2 groups according to the CIN occurrence. Results: A total of 663 patients were enrolled and mean age was 62 +/- 10 years. After the intervention, 45 patients had CIN and 618 patients did not have CIN. Logistic regression analysis was performed to define the parameters of CIN. Male gender, diabetes, UAR, contrast volume, presence of coronary artery disease, and C-reactive protein levels were found significant in univariate analysis. However, only UAR was found significant in multivariate analysis (odds ratio 95% confidence interval: 3.426 (1.059-11.079), (P 1 / 4 0.040)).Therefore, it is the only independent predictor for occurrence of CIN. Conclusions: UAR is a reliable scoring system, which predicts CIN in such patient group. This score is not only cost-effective also simple, which can be easily applied into the clinical practice.
dc.identifier.citationDemirci, G., Şahin, A. A., Altunova, M., Aktemur, T., Atmaca, S., & Yalçın, A. A. (2024). The effect of uric acid and albumin ratio in undergoing lower extremity endovascular interventions for peripheral arterial disease related contrast induced nephropathy. Annals of Vascular Surgery, 108, 452-458.
dc.identifier.doi10.1016/j.avsg.2024.05.032
dc.identifier.endpage458
dc.identifier.issn08905096
dc.identifier.pmid39009115
dc.identifier.scopus2-s2.0-85200157038
dc.identifier.scopusqualityQ2
dc.identifier.startpage452
dc.identifier.urihttp://dx.doi.org/10.1016/j.avsg.2024.05.032
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6844
dc.identifier.volume108
dc.identifier.wosWOS:001288911200001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorŞahin, Ahmet Anıl
dc.language.isoen
dc.publisherElsevier inc.
dc.relation.ispartofAnnals of vascular surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titleThe effect of uric acid and albumin ratio in undergoing lower extremity endovascular interventions for peripheral arterial disease related contrast induced nephropathy
dc.typeArticle

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