Impact of Hyberbaric Oxygen Therapy on Olfactory Function and Bulb Volume in Diabetic Patients with Olfactory Dysfunction

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dc.contributor.authorGürbüz, D.
dc.contributor.authorKesimli, M.C.
dc.contributor.authorBilgili, A.M.
dc.contributor.authorDurmaz, H.Ö.
dc.date.accessioned2024-05-19T14:33:19Z
dc.date.available2024-05-19T14:33:19Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractObjective: Investigating the efficiency of Hyperbaric Oxygen Therapy (HBOT), recommended adjuvant therapy for diabetic neuropathy patients, in changing olfactory bulb volume and function in diabetic patients with olfactory dysfunction. Materials and methods: 12 individuals, from a pool of type-2 diabetes mellitus (DM) patients with diabetic foot, had olfactory dysfunction based on olfaction test results. Olfactory tests and Magnetic Resonance Imaging (MRI) were used to measure and evaluate olfactory bulb volume and function changes in response to HBOT in these 12 patients (comparing Group 1 to Group 2). Similar analysis was carried out to compare the findings to those of 13 healthy patients (Group 3). Results: Patients in Group 1, 2, and 3 were categorized as moderately hyposmic, mildly hyposmic, and normosmic, respectively based on olfaction test results. HBO treatment seems to be efficient as the OBV values and olfaction test results of Group 1 were significantly lower than those of Group 2. Comparison of olfactory tests shows statistically significant improvement in post-treatment odor perception. Conclusion: It has been shown that both olfactory function and OB volumes based on MRI have increased significantly after HBO therapy in diabetic patients with olfactory dysfunction. © 2023, Istanbul University Press. All rights reserved.en_US
dc.description.sponsorshipno financial support.en_US
dc.identifier.doi10.26650/Tr-ENT.2023.1239029
dc.identifier.endpage5en_US
dc.identifier.issn2602-4837
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85166179642en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1en_US
dc.identifier.trdizinid1166265en_US
dc.identifier.urihttps://doi.org/10.26650/Tr-ENT.2023.1239029
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1166265
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4187
dc.identifier.volume33en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherIstanbul University Pressen_US
dc.relation.ispartofTurkish Journal of Ear Nose and Throaten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAnosmiaen_US
dc.subjectDiabetesen_US
dc.subjectHyperbaric Oxygen Therapyen_US
dc.subjectHyposmiaen_US
dc.subjectOlfactory Bulb Volumeen_US
dc.titleImpact of Hyberbaric Oxygen Therapy on Olfactory Function and Bulb Volume in Diabetic Patients with Olfactory Dysfunctionen_US
dc.typeArticleen_US

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