Acanthamoeba keratitis: new hopes for potential interventions for a curable but often refractory disease

Basit Öğe Kaydı
dc.authorscopusidRuqaiyyah Siddiqui / 18635417000
dc.authorscopusidNaveed Ahmed Khan / 7401797675
dc.authorwosidRuqaiyyah Siddiqui / AIF-2100-2022
dc.authorwosidNaveed Ahmed Khan / GWD-0187-2022
dc.contributor.authorAlawfi, Bader Saleem
dc.contributor.authorKhan, Naveed Ahmed
dc.contributor.authorLloyd, David
dc.contributor.authorSiddiqui, Ruqaiyyah
dc.date.accessioned2025-04-18T09:48:15Z
dc.date.available2025-04-18T09:48:15Z
dc.date.issued2024
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractIntroductionOften associated with contact lens wear, Acanthamoeba keratitis is an extremely painful blinding infection that has remained significant despite advances in drug discovery and chemotherapies. Current treatment is intricate and demands early diagnosis, aggressive and prolonged application, and may result in infection recurrence. The latter is due to the ability of the parasite to undergo cellular differentiation and transform into a resistant cyst form or infective trophozoite form. Areas coveredHere, we present a review of our current understanding of emerging therapies and priorities tackling Acanthamoeba keratitis. Literature searches were carried out using bibliographic databases and results sifted and reviewed to present recent findings, challenges and novel opportunities in the development of therapeutic interventions and/or preventative measures against Acanthamoeba keratitis. Expert opinionNanomedicine-based theranostics to combine diagnosis and treatment of Acanthamoeba keratitis offer remarkable opportunity in the development of clinical applications in the management of Acanthamoeba keratitis.
dc.description.sponsorshipUnited States Department of Defense Air Force Office of Scientific Research (AFOSR)
dc.identifier.citationAlawfi, B. S., Khan, N. A., Lloyd, D., & Siddiqui, R. (2024). Acanthamoeba keratitis: new hopes for potential interventions for a curable but often refractory disease. Expert Review of Ophthalmology, (just-accepted).
dc.identifier.doi10.1080/17469899.2024.2370881
dc.identifier.endpage280
dc.identifier.issn1746-9899
dc.identifier.issn1746-9902
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85196748071
dc.identifier.scopusqualityQ3
dc.identifier.startpage271
dc.identifier.urihttp://dx.doi.org/10.1080/17469899.2024.2370881
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6866
dc.identifier.volume19
dc.identifier.wosWOS:001253085300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorKhan, Naveed Ahmed
dc.institutionauthorSiddiqui, Ruqaiyyah
dc.institutionauthoridRuqaiyyah Siddiqui / 0000-0001-9646-6208
dc.institutionauthoridNaveed Ahmed Khan / 0000-0001-7667-8553
dc.language.isoen
dc.publisherRoutledge journals, taylor & francis
dc.relation.ispartofExpert review of ophthalmology
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcanthamoeba
dc.subjectSight-Threatening Amoeba
dc.subjectEye Infection
dc.subjectFree-Living Amoebae
dc.subjectEmerging Therapies
dc.titleAcanthamoeba keratitis: new hopes for potential interventions for a curable but often refractory disease
dc.typeOther

Dosyalar

Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.17 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Cerrahi Tıp Bilimleri Bölümü Diğer Yayınlar Koleksiyonu