The association between symptomatic carotid stenosis and hematological parameters

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dc.authoridEREN, Fettah/0000-0001-6834-0827
dc.authorwosidEREN, Fettah/N-1442-2017
dc.contributor.authorOngun, Gozde
dc.contributor.authorEren, Fettah
dc.contributor.authorOzguncu, Cihat
dc.contributor.authorOzdemir, Gokhan
dc.contributor.authorYildogan, Aydin Talip
dc.contributor.authorCicek, Omer Faruk
dc.contributor.authorOzturk, Serefnur
dc.date.accessioned2024-05-19T14:39:51Z
dc.date.available2024-05-19T14:39:51Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBackground & Objectives: Symptomatic carotid artery stenosis (SCAS) is one of the most important causes of ischemic stroke. We aimed to investigate the relationship between hematological and inflammatory parameters in patients with SCAS and controls. Method: Patients who underwent digital subtraction angiography for SCAS were evaluated retrospectively. Patients with carotid stenosis greater than 50% who had a stroke in the last six months were included in the study. Clinical and sociodemographic characteristics, stent characteristics, filter use, balloon dilatation status, arch type, presence of contralateral occlusion, and complication status were recorded. Hemogram was evaluated using fluorescence flow cytometry. Data were analyzed among patients with SCAS, ischemic stroke patients without stenosis and healthy control group. Results: SCAS was higher in patients with advanced age, male, hypertension, hyperlipidemia, diabetes mellitus, coronary artery disease, and a history of stroke as compared to healthy individuals (p<0.001). Smoking and atrial fibrillation were higher in group without carotid stenosis and who had ischemic stroke (p<0.001). Hemoglobin and hematocrit values were higher in healthy control group (p=0.001). Red blood cell distribution width (RDW) and platelet/lymphocyte ratio (PLR) were higher in SCAS patients (p<0.001); Neutrophil and neutrophil/lymphocyte ratio (NLR) was higher in the group with stroke and without stenosis (p <0.001). There was no relationship between blood parameters and procedure technical features and complications (p> 0.05). Conclusion: Hematologic parameters like PLR, NLR and RDW level are correlated with SCAS. PLR, NLR and RDW value can be an inexpensive and useful biomarker for predicting SCAS.en_US
dc.identifier.doi10.54029/2023ane
dc.identifier.endpage266en_US
dc.identifier.issn1823-6138
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85168814458en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage259en_US
dc.identifier.urihttps://doi.org10.54029/2023ane
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4861
dc.identifier.volume28en_US
dc.identifier.wosWOS:001027573300003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAsean Neurological Assocen_US
dc.relation.ispartofNeurology Asiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectCarotid Stenosisen_US
dc.subjectIschemic Strokeen_US
dc.subjectHematological Parametersen_US
dc.titleThe association between symptomatic carotid stenosis and hematological parametersen_US
dc.typeArticleen_US

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