Endemic Inula Viscosa (L.) Extracts and Their Potential for Both Biosynthesizing Silver Nanoparticles and Anti-microbial Activity

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dc.contributor.authorOzbey, B.O.
dc.contributor.authorCaliskan, G.
dc.date.accessioned2024-05-19T14:33:20Z
dc.date.available2024-05-19T14:33:20Z
dc.date.issued2024
dc.departmentİstinye Üniversitesien_US
dc.description16th Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2023 and 5th International Conference on Medical and Biological Engineering, CMBEBIH 2023 -- 14 September 2023 through 16 September 2023 -- -- 306339en_US
dc.description.abstractGreen synthesis has recently become one of the most popular methods, as it is both low-budget and environmentally friendly. One of the important considerations in green synthesis is to perform an optimization study because it is necessary to understand how different application conditions (pH, incubation time, metal concentration, etc.) can affect the formation of nanoparticles with different morphology and efficiency, underlining the need for optimization of the process. In this study, firstly the endemic Inula Viscosa (L.) plant, popularly known as cancer grass, was extracted using distillation method. Then, silver nanoparticle (AgNPs) biosynthesis was carried out using the extract of Inula Viscosa (L.) plant. Their physicochemical characterization was conducted using Fourier-transformed infrared spectroscopy (FTIR), UV-visible spectrophotometry (UV-Vis), Scanning Electron Microscopy (SEM), and Dynamic Light Scattering (DLS). The time, pH, and AgNO3 concentration, which affect the characteristic and morphological properties of AgNPs, were optimized with the Box Behnken Design (BBD) method, with statistical and experimental design determined by means of a Design Expert statistical software program. The disk diffusion method was also implemented and optimized to increase antimicrobial activity. The study determined the optimal levels of AgNPs, which were green synthesized by Inula Viscosa (L.), provided proof of its antimicrobial properties, and demonstrated their potential to be used as a low-budget aid to new generation clinical treatment methods. © 2024, The Author(s), under exclusive license to Springer Nature Switzerland AG.en_US
dc.identifier.doi10.1007/978-3-031-49068-2_7
dc.identifier.endpage61en_US
dc.identifier.isbn9783031490675
dc.identifier.issn1680-0737
dc.identifier.scopus2-s2.0-85181806426en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage51en_US
dc.identifier.urihttps://doi.org/10.1007/978-3-031-49068-2_7
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4196
dc.identifier.volume94en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Science and Business Media Deutschland GmbHen_US
dc.relation.ispartofIFMBE Proceedingsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAntimicrobial Activityen_US
dc.subjectBiosynthesisen_US
dc.subjectInula Viscosa (L.)en_US
dc.subjectSilver Nanoparticlesen_US
dc.titleEndemic Inula Viscosa (L.) Extracts and Their Potential for Both Biosynthesizing Silver Nanoparticles and Anti-microbial Activityen_US
dc.typeConference Objecten_US

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