Clinical and Pathological Features of Adrenal Myelolipoma and Myelolipomatous Metaplasia Cases in Our Hospital Over 13 Years

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dc.authoridAltintas, Mehmet Mustafa/0000-0002-1522-8687
dc.authoridErdogan, Nusret/0000-0002-0333-8600
dc.authoridSensu, Sibel/0000-0002-4607-780X
dc.authorwosidAltintas, Mehmet Mustafa/AAE-6222-2021
dc.contributor.authorSensu, Sibel
dc.contributor.authorGul, Aylin Ege
dc.contributor.authorKeser, Sevinc Hallac
dc.contributor.authorGurbuz, Yesim Saliha
dc.contributor.authorAltintas, Mehmet
dc.contributor.authorBarisik, Cem Cahit
dc.contributor.authorBarisik, Nagehan Ozdemir
dc.date.accessioned2024-05-19T14:38:53Z
dc.date.available2024-05-19T14:38:53Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBACKGROUND/AIMS: The development and widespread use of abdominal imaging techniques has increased the incidence of unexpected adrenal tumors called adrenal incidentaloma. Adrenal myelolipomas are the second most common incidentalomas. Similar myelolipomatous morphology appears as a secondary degenerative change in other adrenal lesions and is called myelolipomatous metaplasia. This study investigated the adrenal entities of the last 13 years which had myelolipomatous components.MATERIALS AND METHODS: In this retrospective observational study, cases diagnosed as adrenal myelolipoma or myelolipomatous metaplasia between January, 2009 and January, 2022 were re-examined regarding their age, gender, localization, lesion size, and secondary histopathological changes, accompanying pathological diagnoses as well as clinical and radiological data.RESULTS: Eleven adrenal myelolipoma cases and 6 myelolipomatous metaplasia cases were detected. In myelolipomas, the mean age was 55.45 years, 73% were female and 82% were located on the right side. The lesions were encapsulated and their mean size was 7 cm. One case had a diagnosis of subclinical Cushing's syndrome and the others were hormonally inactive. Some cases were accompanied with hypertension (27%), type 2 diabetes (18%), and asthma (18%). All myelolipomatous metaplasias, which are non-encapsulated, were detected in adrenocortical adenomas. The mean age was 58 years; nonencapsulated and 67% were located on the right side with no gender predilection. Concomitant hypertension (50%), diabetes /33%, and asthma (33%) were frequent.CONCLUSION: Adrenal myelolipoma and myelolipomatous metaplasia both contain adipose and myeloid components. Myelolipoma is a benign and encapsulated neoplasia which is usually detected incidentally. They frequently coexist with chronic diseases such as hypertension, diabetes and asthma.en_US
dc.identifier.doi10.4274/cjms.2022.2022-13
dc.identifier.endpage65en_US
dc.identifier.issn2149-7893
dc.identifier.issn2536-507X
dc.identifier.issue1en_US
dc.identifier.startpage60en_US
dc.identifier.trdizinid1177017en_US
dc.identifier.urihttps://doi.org10.4274/cjms.2022.2022-13
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1177017
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4638
dc.identifier.volume8en_US
dc.identifier.wosWOS:000946014500010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofCyprus Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAdrenalen_US
dc.subjectMyelolipomaen_US
dc.subjectMyelolipomatous Metaplasiaen_US
dc.titleClinical and Pathological Features of Adrenal Myelolipoma and Myelolipomatous Metaplasia Cases in Our Hospital Over 13 Yearsen_US
dc.typeArticleen_US

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