Determining the temporal factors of survival associated with brain and nervous system cancer patients: A hybrid machine learning methodology

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Tarih

2023

Dergi Başlığı

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Cilt Başlığı

Yayıncı

Routledge Journals, Taylor & Francis Ltd

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Purpose Although different cancer types have been investigated from the perspective of biomedical sciences, machine learning-based studies have been scant. The present study aims to uncover the temporal effects of factors that are important for brain and central nervous system (BCNS) cancer survival, by proposing a machine learning methodology. Methods Several feature selection, data balancing, and machine learning algorithms (in addition to the sensitivity analysis) were employed to analyze the dynamic (i.e. varying) effects of several feature sets on the survival outputs. Results The results show that Gradient Boosting (GB) along with Logistic Regression (LR) and Artificial Neural Networks (ANN) outperform the other classification algorithms in this study. Furthermore, it has been observed that the importance of several features/variables varies from 1- to 5- and 10-year survival predictions. Conclusion Although the proposed hybrid methodology is validated on a large and feature-rich BCNS cancer data set, it can also be utilized to study survival prognostics of other cancer or chronic disease types.

Açıklama

Anahtar Kelimeler

Temporal Effect, Machine Learning, Healthcare Analytics, Parsimonious Model, Brain And Other Nervous System Cancer, Predictive Modeling

Kaynak

International Journal of Healthcare Management

WoS Q Değeri

N/A

Scopus Q Değeri

Q2

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