The effects of vitamin d and microfracture surgery technique on calcium and phosphorus: a pilot study

dc.authoridDenizhan Karış / 0000-0002-5976-4107en_US
dc.authorscopusidDenizhan Karış / 56449066200
dc.authorwosidDenizhan Karış / N-5001-2019
dc.contributor.authorTarhan, Duygu
dc.contributor.authorTok, Okan
dc.contributor.authorKarış, Denizhan
dc.contributor.authorErcan, Alev Meltem
dc.date.accessioned2020-09-25T13:51:46Z
dc.date.available2020-09-25T13:51:46Z
dc.date.issued2020en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: Vitamin D has an important effect on calcium (Ca) and phosphorus (P) metabolism and bone health. It helps regulate the ratio of Ca and P. The aim of this study was to investigate the effects of vitamin D and minor surgical stress on Ca and P levels in the liver, kidneys, and serum in 24 New Zealand rabbits with cartilage defects. Methods: Experimental groups of MFS (only microfracture surgery), Vit D (only oral vitamin D supplementation), and MFS+Vit D (both microfracture surgery and oral vitamin D supplementation) were created. The levels of Ca and P in serum, liver, and kidney samples were measured using a spectrophotometric method. Results: The kidney Ca/P ratio was lower and the serum Ca/P ratio was higher in the MFS+Vit D groups than in the control group. The serum P level was significantly lower in the MFS and MFS+Vit D groups when compared with the control group. Conclusion: To the best of our knowledge, this is a novel study examining microfracture surgery and the effect on Ca and P. The Ca/P ratio revealed clinically valuable information about the important balance between Ca/P ratio and the adequacy of vitamin D. Vitamin D supplementation before microfracture surgery may be beneficial and may prevent a de creased Ca/P ratio due to the effect of surgical stress.en_US
dc.identifier.citationTARHAN D,TOK O,KARİS D,ERCAN A. M (2020). The effects of vitamin D and microfracture surgery technique on calcium and phosphorus: A pilot study. International Journal of Medical Biochemistry, 3(1), 19 - 23. Doi: 10.14744/ijmb.2019.38258en_US
dc.identifier.doi10.14744/ijmb.2019.38258en_US
dc.identifier.endpage23en_US
dc.identifier.issn2587-2362en_US
dc.identifier.issn2618-642Xen_US
dc.identifier.issue1en_US
dc.identifier.startpage19en_US
dc.identifier.trdizinid358660en_US
dc.identifier.urihttps://doi.org/10.14744/ijmb.2019.38258
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1114
dc.identifier.volume3en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorKarış, Denizhan
dc.language.isoenen_US
dc.relation.ispartofInternational Journal of Medical Biochemistryen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCalciumen_US
dc.subjectCartilage Defectsen_US
dc.subjectMicrofracture Surgery Techniqueen_US
dc.subjectPhosphorusen_US
dc.subjectRabbiten_US
dc.subjectVitamin Den_US
dc.titleThe effects of vitamin d and microfracture surgery technique on calcium and phosphorus: a pilot studyen_US
dc.typeArticleen_US

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