Usefulness of Age, Creatinine and Ejection Fraction- Modification of Diet in Renal Disease Score for Predicting Survival in Patients with Heart Failure

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dc.authoridYILMAZ, Mehmet Birhan/0000-0002-8169-8628
dc.authorwosidYILMAZ, Mehmet Birhan/Y-1372-2019
dc.contributor.authorGuvenc, Rengin Cetin
dc.contributor.authorGuvenc, Tolga Sinan
dc.contributor.authorCavusoglu, Yuksel
dc.contributor.authorTemizhan, Ahmet
dc.contributor.authorYilmaz, Mehmet Birhan
dc.date.accessioned2024-05-19T14:42:18Z
dc.date.available2024-05-19T14:42:18Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBackground: While many risk models have been developed to predict prognosis in heart failure (HF), these models are rarely useful for the clinical practitioner as they include multiple variables that might be time-consuming to obtain, they are usually difficult to calculate, and they may suffer from statistical overfitting.Objectives: To investigate whether a simpler model, namely the ACEF-MDRD score, could be used for predicting one-year mortality in HF patients.Methods: 748 cases within the SELFIE-HF registry had complete data to calculate the ACEF-MDRD score. Patients were grouped into tertiles for analyses. For all tests, a p-value <0.05 was accepted as significant.Results: Significantly more patients within the ACEF-MDRD (high) tertile (30.0%) died within one year, as compared to other tertiles (10.8% and 16.1%, respectively, for ACEF-MDRD (low) and ACEF-MDRD (med) , p<0.001 for both comparisons). There was a stepwise decrease in one-year survival as the ACEF-MDRD score increased (log-rank p<0.001). ACEF-MDRD was an independent predictor of survival after adjusting for other variables (OR: 1.14, 95%CI:1.04 - 1.24, p=0.006). ACEF-MDRD score offered similar accuracy to the GWTG-HF score for predicting one-year mortality (p=0.14).Conclusions: ACEF-MDRD is a predictor of mortality in patients with HF, and its usefulness is comparable to similar yet more complicated models.en_US
dc.identifier.doi10.36660/abc.20230158
dc.identifier.issn0066-782X
dc.identifier.issn1678-4170
dc.identifier.issue12en_US
dc.identifier.pmid38232244en_US
dc.identifier.urihttps://doi.org10.36660/abc.20230158
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5224
dc.identifier.volume120en_US
dc.identifier.wosWOS:001146818500001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherArquivos Brasileiros Cardiologiaen_US
dc.relation.ispartofArquivos Brasileiros De Cardiologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectHeart Failureen_US
dc.subjectMortalityen_US
dc.subjectSurvivorship.en_US
dc.titleUsefulness of Age, Creatinine and Ejection Fraction- Modification of Diet in Renal Disease Score for Predicting Survival in Patients with Heart Failureen_US
dc.typeArticleen_US

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