Therapeutic targeting of molecular pathways in colorectal cancer

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dc.authoridEbru Nur Ay / 0000-0001-7121-4362en_US
dc.authorscopusidEbru Nur Ay / 57209852424
dc.authorwosidEbru Nur Ay / L-5910-2018en_US
dc.contributor.authorAy, Ebru Nur
dc.date.accessioned2022-06-28T07:14:43Z
dc.date.available2022-06-28T07:14:43Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Laboratuvar Teknikleri Bölümüen_US
dc.description.abstractMutations in tumor suppressor genes, cell signaling, and genes associated with DNA repair lead to onset of colorectal cancer (CRC). Even though most CRC patients get clinical benefits from conventional treatments such as chemotherapy and radiotherapy, treatment success is still not at the desired level despite recent advances in CRC treatments. Therefore, further elucidation of the molecular signaling pathways involved in CRC progression will allow developing targeted therapies. With the detection of signaling pathways that lead to cancer progression and development of the successful treatment methods targeting these pathways, the progression of the disease can be prevented. This review provides an overview of the therapeutic roles of potential molecular targets in recent preclinical and clinical studies in CRC treatment.en_US
dc.identifier.citationNur Ay Ay. THERAPEUTIC TARGETING OF MOLECULAR PATHWAYS IN COLORECTAL CANCER. Exp Oncol. 2022 May;44(1):2-6. doi: 10.32471/exp-oncology.2312-8852.vol-44-no-1.17455. PMID: 35548959.en_US
dc.identifier.doi10.32471/exp-oncology.2312-8852.vol-44-no-1.17455en_US
dc.identifier.issue1en_US
dc.identifier.pmid35548959en_US
dc.identifier.scopus2-s2.0-85130633338en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttp://doi.org/10.32471/exp-oncology.2312-8852.vol-44-no-1.17455
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2947
dc.identifier.volume44en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAy, Ebru Nur
dc.language.isoenen_US
dc.publisherMorionLLCen_US
dc.relation.ispartofExperimental Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColorectal Cancer Drugsen_US
dc.subjectMolecular Targeted Therapyen_US
dc.subjectCRC Signaling Pathwaysen_US
dc.subjectTumor Biomarkersen_US
dc.titleTherapeutic targeting of molecular pathways in colorectal canceren_US
dc.typeArticleen_US

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