Preparation of quercetin incorporated photocrosslinkable methacrylated gelatin/methacrylated kappa-carrageenan antioxidant hydrogel wound dressings

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dc.authoridAyça Bal Öztürk / 0000-0002-6502-528Xen_US
dc.authoridGülşah Torkay / 0000-0002-6803-494X
dc.authorscopusidGülşah Torkay / 57753937500
dc.authorscopusidAyça Bal Öztürk / 57062000100
dc.authorwosidAyça Bal Öztürk / M-4472-2018en_US
dc.authorwosidGülşah Torkay / IUP-3797-2023
dc.contributor.authorÖzbaş, Zehra
dc.contributor.authorTorkay, Gülşah
dc.contributor.authorBal Öztürk, Ayça
dc.contributor.authorÖzkahraman, Bengi
dc.date.accessioned2022-09-13T12:38:56Z
dc.date.available2022-09-13T12:38:56Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Temel Bilimleri Bölümüen_US
dc.description.abstractWound dressings with antioxidant potential have attracted remarkable concerns for wound healing. The purpose of this work is to investigate blank, and quercetin loaded photocrosslinkable methacrylated gelatin (GelMA)/methacrylated kappa-carrageenan (KapMA) hydrogel. Wound dressings were produced by the photocrosslinking method in the presence of a photoinitiator. Quercetin was incorporated in photocrosslinkable GelMA/KapMA wound dressings with different ratios. Besides, Fourier Transform Infrared Spectroscopy, thermal gravimetric analysis, swelling, and degradation tests were performed for characterization studies of the hydrogel wound dressings. The release of quercetin from GelMA/KapMA wound dressings was investigated at a physiological pH value of 7.4 at 37 degrees C. The antioxidant activity of the hydrogel dressings was further evaluated by 2,2-diphenyl-1-picrylhydrazyl method. Biocompatibility of wound dressings was assessed using MTT assay tests on NIH-3T3 cell line, which evaluated its suitability in biomaterial applications. The obtained results indicated that quercetin incorporated photocrosslinked GelMA/KapMA wound dressings provide antioxidant activity, and they could be the ability for the potential wound dressings applications.en_US
dc.identifier.citationOzbas, Z., Torkay, G., Bal-Ozturk, A., Ozkahraman, B. (2022). Preparation of quercetin incorporated photocrosslinkable methacrylated gelatin/methacrylated kappa-carrageenan antioxidant hydrogel wound dressings. Cheminal Papers.en_US
dc.identifier.doi10.1007/s11696-022-02426-3en_US
dc.identifier.issn0366-6352en_US
dc.identifier.scopus2-s2.0-85136535424en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s11696-022-02426-3
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3138
dc.identifier.wosWOS:000843975500003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBal Öztürk, Ayça
dc.institutionauthorTorkay, Gülşah
dc.language.isoenen_US
dc.publisherSPRINGER INT PUBL AGen_US
dc.relation.ispartofCHEMICAL PAPERSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMethacylated Gelatinen_US
dc.subjectMethacrylated Kappa-Carrageenanen_US
dc.subjectAntioxidanten_US
dc.subjectWound Dressingen_US
dc.subjectQuercetinen_US
dc.titlePreparation of quercetin incorporated photocrosslinkable methacrylated gelatin/methacrylated kappa-carrageenan antioxidant hydrogel wound dressingsen_US
dc.typeArticleen_US

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