Determination of protein amount in nanosized synthetic liposomes by Surface Enhanced Raman Spectroscopy (SERS)

Basit Öğe Kaydı
dc.authoridŞeyma Parlatan / 0000-0003-2355-4674en_US
dc.authorscopusidŞeyma Parlatan / 57267804700en_US
dc.authorwosidŞeyma Parlatan / ABF-3308-2020en_US
dc.contributor.authorParlatan, Şeyma
dc.date.accessioned2024-02-21T08:04:39Z
dc.date.available2024-02-21T08:04:39Z
dc.date.issued9en_US
dc.departmentİstinye Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Radyoterapi Programıen_US
dc.description.abstractAccurate characterization of synthetic liposomes is essential since they give information about the vesic ular structures in bodily fluids such as extracellular vesicles. The characterization tasks are generally the determina tion of the sizes of the liposomes and the profiling of the liposomes' content. Optical tweezers and Surface Enhanced Raman Spectroscopy (SERS) were used to profile the nanosized liposomes. The size distribution of the trapped lip osomes (140 nm on average) was found by using Einstein's Brownian motion equation, consistent with the size dis tribution obtained from dynamic light scattering measurements. Besides, Gramicidin-encapsulated liposomes were measured using SERS, and statistically significant differentiation was found in Raman intensities between liposome populations with altering concentrations of proteins. This study uniquely measured size distributions of nano-sized liposomes with conventional optical tweezers (without plasmonics) and determined the chemical differences between empty and protein encapsulated liposomes with high accuracy using Raman spectroscopy.en_US
dc.identifier.citationParlatan, Ş. Determination of Protein Amount in Nanosized Synthetic Liposomes by Surface Effect Raman Spectroscopy (SERS). Journal of Advanced Research in Natural and Applied Sciences, 9(4), 912-922.en_US
dc.identifier.doi10.28979/jarnas.1284172en_US
dc.identifier.endpage922en_US
dc.identifier.issue4en_US
dc.identifier.startpage912en_US
dc.identifier.trdizinid1213930en_US
dc.identifier.urihttps://doi.org/10.28979/jarnas.1284172
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4017
dc.identifier.volume9en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorParlatan, Şeyma
dc.language.isoenen_US
dc.publisherÇanakkale Onsekiz Mart Universityen_US
dc.relation.ispartofJournal of Advanced Research in Natural and Applied Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal - Editör Denetimli Dergien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLiposomeen_US
dc.subjectOptical Trappingen_US
dc.subjectSurface Enhanced Raman Spectroscopyen_US
dc.subjectGramicidinen_US
dc.subjectProtein Determinationen_US
dc.titleDetermination of protein amount in nanosized synthetic liposomes by Surface Enhanced Raman Spectroscopy (SERS)en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
10.28979-jarnas.1284172-3088152.pdf
Boyut:
1.01 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Radyoterapi Programı Makale Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu