Demographic, clinical, and laboratory characteristics of elderly onset psoriatic arthritis

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dc.authoridŞenol Kobak / 0000-0001-8270-640X
dc.authorscopusidŞenol Kobak / 12782228700
dc.authorwosidŞenol Kobak / AAO-2482-2020
dc.contributor.authorKobak, Şenol
dc.contributor.authorOrman, Mehmet Akif
dc.date.accessioned2020-08-30T20:08:09Z
dc.date.available2020-08-30T20:08:09Z
dc.date.issued2017
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAnnual European Congress of Rheumatology -- JUN 14-17, 2017 -- Madrid, SPAINen_US
dc.description.abstractBackground: Psoriatic arthritis (PsA) is a chronic in?amatory disease characterized with axial and peripheral joints involvement. It is rarely affects patients older than 65 years old. Objectives: The purpose of this study is to compare and evaluate the demographic,clinicalandlaboratoryfeaturesofelderly-onsetpsoriaticarthritis(EOPsA) and young-onset (YOPsA) patients. Methods: One hundred and eighty patients diagnosed with PsA according to CASPAR criteria and followed-up in single center were included in this study. The patients with initial symptoms started after age 65 were accepted as EOPsA. Demographic,clinical,andlaboratorydataandthemedicationswhichthepatients recieved were recorded and retrospectively evaluated. Results: Nineteen (10.5%)of 180 patients were diagnosed as EOPsA, and 161 (89.5%) patients were evaluated as YOPsA. Mean patient age was 42.1years for YOPsA group and 68.3years for elderly onset group. Mean duration of disease was 5.6 years for early onset group and 1.3 years for elderly onset group (p=0.001). Fourteen (73.3%) of 19 EOPsA patients were female and 5 of them were male. Higher rates of fatique, pain scores, comorbid diseases and acute phase reactants were detected in EOPsA patients comparing to YOPsA (p=0.000, p=0.000, p=0.001 and p=0.001 respectively). YOPsA patients have more dactilitis, nail involvement, elevated PASI scores, and smoking habitus when comparedwithEOPsApatients(p=0.019,p=0.03,p=0.005,p=0.004respectively). In terms of the treatment options chosen, there was no signi?cant difference in the use of non-steroidal anti-in?ammatory drugs (NSAIDs), corticosteroids (CS), methotrexate (MTX), and sulfasalazine (SSL), but there was a more frequent use of anti-tumor necrosis factor -alpha in YOPsA group. Conclusions: Herein we showed that YOPsA and EOPsA patients may have different demographic, clinical, and laboratory features. EOPsA patients are characterized with higher rates of fatique, pain scores, comorbid diseases, and acute phase reactants and less dactilitis, nail involvement and anti-TNF-alpha usage.en_US
dc.identifier.citationKobak, S., & Orman, M. (2017). SAT0476 Demographic, clinical, and laboratory characteristics of elderly onset psoriatic arthritis.en_US
dc.identifier.doi10.1136/annrheumdis-2017-eular.1378en_US
dc.identifier.endpage955en_US
dc.identifier.issn0003-4967en_US
dc.identifier.issn1468-2060en_US
dc.identifier.startpage955en_US
dc.identifier.urihttps://doi.org/10.1136/annrheumdis-2017-eular.1378
dc.identifier.urihttps://hdl.handle.net/20.500.12713/893
dc.identifier.volume76en_US
dc.identifier.wosWOS:000413181402762en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorKobak, Şenolen_US
dc.language.isoenen_US
dc.publisherBmj Publishing Groupen_US
dc.relation.ispartofAnnals of The Rheumatic Diseasesen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleDemographic, clinical, and laboratory characteristics of elderly onset psoriatic arthritisen_US
dc.typeConference Objecten_US

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