First report of t(1;9)(q21;q34) in Fanconi anemia as a preceeding chromosomal aberration before leukemia development
Küçük Resim Yok
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
KUWAIT MEDICAL ASSOC
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Patients with Fanconi anemia (FA) tend to develop various hematologic and solid tumors. Cytogenetic abnormalities such as translocations of chromosome 1q, monosomy 5 and 7, trisomy 10, gains of 3q and t(8;21) have been reported in patients with FA who developed hematological malignancies. Since survival is low after the development of leukemia in FA patients, the follow-up for leukemia progression is very important. For this reason, cytogenetic anomalies that can be used as biomarkers in the development of leukemia are needed. Herein, we describe a patient with FA who developed acute myeloid leukemia with der(9)t(1;9) (q21;q34) for the first time.
Açıklama
Anahtar Kelimeler
Acute Myeloid Leukemia, Childhood Leukemia, Chromosomal Abnormalities, Fanconi Anemia, Rare Translocation
Kaynak
KUWAIT MEDICAL JOURNAL
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
54
Sayı
1
Künye
Bozkurt, S., Unal, S., Gumruk, F. (2022). First report of t(1;9)(q21;q34) in Fanconi anemia as a preceeding chromosomal aberration before leukemia development. Kuwait Medical Journal, 54(1), 119-122.
