Thyroid volume in young males with idiopathic hypogonadotropic hypogonadism versus young healthy males

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Küçük Resim

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

NOBEL ILAC

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Objective: To evaluate the differences in thyroid volume and thyroid functions between male patients newly diagnosed with idiopathic hypogonadotropic hypogonadism (IHH) and healthy males. Material and Method: A total of 51 consecutively diagnosed male patients with IHH (mean age: 30.1 +/- 8.9 years) and 36 body mass index (BMI)- and age-matched healthy controls (mean age: 31.3 +/- 5.9 years) were included in the study. All the subjects resided in the same region where mild iodine deficiency was present. Patients with thyroid diseases were excluded. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), IGF-1, prolactin, cortisol, total testosterone, free testosterone, free T4 (fT4), free T3 (fT3), TSH, anti-TPO, and anti-TG were evaluated. Thyroid volumes (TV) were measured using a high-resolution. ultrasound operated by an experienced endocrinologist. Results: FSH, LH, total testosterone and free testosterone were lower in patients with IHH than in the control subjects (p<0.05). TSH, fT4, fT3, anti-TPQ and anti-TG were found to be similar in both groups (p>0.05). Thyroid volume of patients with IHH (mean value of TV=11, 0 +/- 6.2 mL) was significantly smaller than in the control subjects (mean value of TV=18, 6 +/- 8.1 mL) (p=0.001). Conclusion: Young males with newly diagnosed IHH have smaller thyroid volume than healthy males. Thyroid function tests were similar in both groups.

Açıklama

Anahtar Kelimeler

Hypogonadism, Thyroid Gland, Gonadotropins, Thyroid Function Tests

Kaynak

NOBEL MEDICUS

WoS Q Değeri

Q4

Scopus Q Değeri

Q4

Cilt

17

Sayı

1

Künye

Karakılıç, E., Unal, I. M., Ayçiçek, I. B., Berker, I. D., Tuna, I. M. M., Güler, I. S., & Başaran, I. M. N. (2021). THYROID VOLUME IN YOUNG MALES WITH IDIOPATHIC HYPOGONADOTROPIC HYPOGONADISM VERSUS YOUNG HEALTHY MALES. Nobel Medicus Journal, 17(1).