Extraction, characterization, and biocompatibility evaluation of type i collagen from chicken feet skin

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dc.authorscopusidBerivan Çecen / 24461480700
dc.authorwosidBerivan Çeçen / Q-4203-2019
dc.contributor.authorZourazema, Sevda
dc.contributor.authorZendeh, Zahra
dc.contributor.authorAksun, Elif Tuğçe
dc.contributor.authorGörgün, Büşra
dc.contributor.authorGüzel, Fatma Doğan
dc.contributor.authorÇeçen, Berivan
dc.date.accessioned2025-04-17T13:44:35Z
dc.date.available2025-04-17T13:44:35Z
dc.date.issued2025
dc.departmentİstinye Üniversitesi, Lisansüstü Eğitim Enstitüsü, Sağlık Bilimleri, Kök Hücre ve Doku Mühendisliği Programı
dc.description.abstractThe study focused on extracting type I collagen, a protein derived from chicken feet skin, for applications in the biomedical and cosmetic industries. The research thoroughly explored the extraction methodology and characterization techniques and assessed the biocompatibility of the collagen. Acid extraction yielded substantial amounts of type I collagen with an efficiency of 11.35%. The characterization process involved various analyses, including FTIR, SDS-PAGE, western blot, and SEM imaging, to evaluate purity, structural integrity, and morphology. In vitro testing confirmed the biocompatibility of the extracted collagen, indicating its potential as a natural polymer for medical studies. The collagen extracted from chicken feet skin demonstrated significant bioactivity, positioning it as a promising polymer for tissue engineering, wound healing, and cosmetic applications. This study underlines the importance of developing biocompatible biomaterials and provides valuable insights into a sustainable source of collagen from animal by-products.
dc.identifier.citationZourazema, S., Zendeh, Z., Aksun, E. T., Gorgun, B., Guzel, F. D., Cecen, B., & Kozaci, L. D. (2025). Extraction, Characterization, and Biocompatibility Evaluation of Type I Collagen from Chicken Feet Skin. Biomedical Materials & Devices, 1-15.
dc.identifier.doi10.1007/s44174-024-00266-1
dc.identifier.issn27314812
dc.identifier.scopus2-s2.0-85217155552
dc.identifier.urihttp://dx.doi.org/10.1007/s44174-024-00266-1
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6280
dc.indekslendigikaynakScopus
dc.institutionauthorÇeçen, Berivan
dc.institutionauthoridBerivan Çecen / 0000-0002-0081-2004
dc.language.isoen
dc.publisherSpringer nature
dc.relation.ispartofBiomedical materials and devices
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBiocompatibility
dc.subjectChicken Foot Skin
dc.subjectType I Collagen Extraction
dc.titleExtraction, characterization, and biocompatibility evaluation of type i collagen from chicken feet skin
dc.typeArticle

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